Results 61 to 70 of about 3,214 (169)
The SlyD metallochaperone targets iron-sulfur biogenesis pathways and the TCA cycle
mBio, 2023 Control of protein folding is a conserved function in all domains of life. The ubiquitous peptidyl-prolyl cis-trans isomerases (PPIases) catalyze the cis/trans-isomerization of peptidyl-prolyl bonds, often a rate-limiting step for protein folding ...
Milica Denic +5 more
doaj +1 more source
Emergence of Francisella novicida Bacteremia, Thailand
Emerging Infectious Diseases, 2008 We report isolation of Francisella novicida–causing bacteremia in a woman from Thailand who was receiving chemotherapy for ovarian cancer. The organism was isolated from blood cultures and identified by 16S rDNA and PPIase gene analyses.
Amornrut Leelaporn +4 more
doaj +1 more source
FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
Cell Reports, 2020 Summary: Cancer therapy is limited, in part, by lack of specificity. Thus, identifying molecules that are selectively expressed by, and relevant for, cancer cells is of paramount medical importance. Here, we show that peptidyl-prolyl-cis-trans-isomerase (
Giorgio Ramadori +17 more
doaj +1 more source
Molecular Plant Pathology, Volume 27, Issue 5, May 2026.ParPMC interactors were screened, highlighting eEF1A proteins; co‐localization and VIGS show their role in PPV infection and sharka susceptibility. ABSTRACT Sharka, caused by Potyvirus plumpoxi (plum pox virus, PPV), is the most destructive viral disease affecting Prunus species worldwide.
Ángela Polo‐Oltra +5 more
wiley +1 more source
Identification of Conus Peptidylprolyl Cis-Trans Isomerases (PPIases) and Assessment of Their Role in the Oxidative Folding of Conotoxins [PDF]
Journal of Biological Chemistry, 2010 Peptidylprolyl cis-trans isomerases (PPIases) are ubiquitous proteins that catalyze the cis-trans isomerization of prolines. A number of proteins, such as Drosophila rhodopsin and the human immunodeficiency viral protein HIV-1 Gag, have been identified as endogenous substrates for PPIases.
Helena, Safavi-Hemami +4 more
openaire +2 more sources
The Plant Genome, Volume 19, Issue 1, March 2026.Abstract Identifying genomic regions linked to yield and quality is crucial for sorghum (Sorghum bicolor L.) improvement, but limited studies on its genome and diversity hinder breeding efforts. This study aimed to identify phenotypic variance and common quantitative trait nucleotides (QTNs) associated with genomic regions linked with grain yield and ...
Chalachew Endalamaw +7 more
wiley +1 more source
Pediatric Allergy and Immunology, Volume 37, Issue 3, March 2026.Abstract Background Panallergens are ubiquitously expressed molecules that may drive IgE sensitization across diverse allergen sources, thereby shaping complex clinical phenotypes such as asthma and pollen–food allergy syndrome (PFAS). Although several panallergen families have been extensively characterized, unexplained sensitization patterns are ...
Wilhelm Sponholz +36 more
wiley +1 more source
Scientific Reports, 2019 Pin1, a polypeptide proline isomerase parvulin, plays a key role in Alzheimer’s disease (AD), common tumors and cancers. Two conservative histidine residues, His59 and His157, are important for maintaining the stability of the PPIase domain.
Wang Wang +6 more
doaj +1 more source
Molecules, 2017 Allosteric communication among domains in modular proteins consisting of flexibly linked domains with complimentary roles remains poorly understood. To understand how complementary domains communicate, we have studied human Pin1, a representative modular
Jing Wang +5 more
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 3, Page 1598-1616, March 2026.ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith +5 more
wiley +1 more source