BiomoleculesMicrobial infections pose a significant global health threat, affecting millions of individuals and leading to substantial mortality rates. The increasing resistance of microorganisms to conventional treatments requires the development of novel ...
Mai M. Labib +9 more
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Development of an Engineered Bacterial Endophyte: Promoting Plant Growth Through Pyrroloquinoline Quinone (PQQ) Synthesis [PDF]
MicroorganismsEndophytic bacteria are a group of microorganisms that can intercellularly colonize plant hosts without causing apparent damage or disease. Our previous works found that a pyrroloquinoline quinone (PQQ)-producing endophyte could promote plant growth and ...
Ti Fang +7 more
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Dietary Pyrroloquinoline Quinone Addition Alleviated Weaning Stress via Modulation of Gut Microbiota and Metabolic Profiles in Weaned Piglets [PDF]
AnimalsWeaning stress in piglets severely restricts swine production efficiency due to growth retardation, immune suppression, and intestinal dysfunction. This study investigated the effects of dietary pyrroloquinoline quinone (PQQ) on 36 weaned piglets (22 ± 1
Haocheng Xu +9 more
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Pyrroloquinoline quinone promotes porcine oocyte maturation and subsequent embryo development by enhancing lipid metabolism and improving mitochondrial function [PDF]
Animal BioscienceObjective The present study evaluated the beneficial effects of pyrroloquinoline quinone (PQQ) on in vitro maturation (IVM) of porcine oocyte and subsequent early embryo development.
Zehua Zhang, Zhigang Gao, Zhenwei Jia
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Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms. [PDF]
PLoS ONETo investigate the effect of pyrroloquinoline quinone (PQQ) on skin aging in the Bmi-1 KO mice and its underlying mechanisms, we administered a normal diet to both Wild type mice (WT) and Bmi-1 KO mice, while supplementing the diet of Bmi-1 KO mice with ...
Bin Li +3 more
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Pyrroloquinoline Quinone Improved Boar Sperm Quality via Maintaining Mitochondrial Function During Cryopreservation [PDF]
AntioxidantsDue to oxidative damage and mitochondrial dysfunction, boar semen cryopreservation remains a significant challenge. This study investigates the effects of pyrroloquinoline quinone (PQQ), a mitochondrial-targeted antioxidant, on the post-thaw boar sperm ...
Shanpeng Wang +6 more
doaj +2 more sources
Pyrroroquinoline Quinone (PQQ) Improves the Quality of Holstein Bull Semen during Cryopreservation [PDF]
AnimalsCryopreserved semen is extensively utilized in the artificial insemination (AI) of domestic animals; however, suboptimal conception rates due to oxidative damage following AI continue to pose a challenge.
Hai Wang +7 more
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Novel Pyrroloquinoline Quinone-Modified Cerium Oxide Nanoparticles and Their Selective Cytotoxicity Under X-Ray Irradiation [PDF]
AntioxidantsIonizing radiation leads to the development of oxidative stress and damage to biologically important macromolecules (DNA, mitochondria, etc.), which in turn lead to cell death.
Elizaveta A. Zamyatina +3 more
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npj Aging, 2022 The aim of this study was to investigate the effects of pyrroloquinoline quinone (PQQ), an oxidoreductase cofactor, on the H 2 O 2 -induced premature senescence model in HEI-OC1 auditory cells and to elucidate its mechanism of action in vitro. Cells were
Ying Gao +4 more
semanticscholar +2 more sources
Frontiers in Neuroscience, 2022 The enteric nervous system (ENS) is important for the intestinal barrier to defend and regulate inflammation in the intestine. The aim of this study was to investigate the effect of pyrroloquinoline quinone (PQQ) on regulating neuropeptide secretion by ...
Chenyu Shi +8 more
doaj +1 more source