Results 21 to 30 of about 2,483 (155)

Pyrroloquinoline Quinone Reprograms the Single-Cell Landscape of Immune Aging in Hematopoietic Immune System. [PDF]

Aging Cell
This study demonstrates that aging induces oxidative stress and inflammation in the hematopoietic immune system, resulting in immune homeostasis dysfunction, including alterations in B cells and hematopoietic stem cells, senescent cells (SnCs) accumulation, and senescence‐associated secretory phenotypes (SASPs) production. Notably, the study highlights
Liu X, Zhang C, Lv J, Liu Y, Gu C, Gao Y, Ding W, Chen H, Xu N, Yin H, Su W, Xu Z.   +11 more
europepmc   +2 more sources

Biotransformation of Deoxynivalenol by a Dual-Member Bacterial Consortium Isolated from Tenebrio molitor Larval Feces

Toxins, 2023
In this study, a dual-member bacterial consortium with the ability to oxidize deoxynivalenol (DON) to 3-keto-DON, designated SD, was first screened from the feces of Tenebrio molitor larvae. This consortium consisted of Pseudomonas sp. SD17-1 and Devosia
Yang Wang, Donglei Zhao, Wei Zhang, Songxue Wang, Kai Huang, Baoyuan Guo   +5 more
doaj   +1 more source

Evidence for PQQ as cofactor in 3,4‐dihydroxyphenylalanine (dopa) decarboxylase of pig kidney [PDF]

FEBS Letters, 1988
Pig kidney 3,4‐dihydroxyphenylalanine (dopa) decarboxylase (EC 4.1.1.28) was purified to homogeneity. Treatment of the enzyme with phenylhydrazine (PH) according to a procedure developed for analysis of quinoproteins gave products which were identified as the hydrazone of pyridoxal phosphate (PLP) and the C(5)‐hydrazone of pyrroloquinoline quinone (PQQ)
Groen, Barend W., van der Meer, Robert A., Duine, Joannis A.   +2 more
openaire   +2 more sources

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

Journal of Animal Science and Biotechnology, 2021
Background Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in
Caiyun Huang, Zijuan Fan, Dandan Han, Lee J. Johnston, Xi Ma, Fenglai Wang   +5 more
doaj   +1 more source

Phenylhydrazine as probe for cofactor identification in amine oxidoreductases Evidence for PQQ as the cofactor in methylamine dehydrogenase [PDF]

FEBS Letters, 1987
Homogeneous methylamine dehydrogenase (primary‐amine:(acceptor) oxidoreductase (deaminating), EC 1.4.99.3, MADH) from the bacterium Thiobacillus versutus was treated with the inhibitor phenylhydrazine (PH). Derivatization of the cofactor in MADH took place in a fast reaction to give compound I.
van der Meer, Robert A., Jongejan, Jacob A., Duine, Johannis A.   +2 more
openaire   +2 more sources

Adaptive evolutionary strategy coupled with an optimized biosynthesis process for the efficient production of pyrroloquinoline quinone from methanol

Biotechnology for Biofuels and Bioproducts, 2023
Background Pyrroloquinoline quinone (PQQ), a cofactor for bacterial dehydrogenases, is associated with biological processes such as mitochondriogenesis, reproduction, growth, and aging.
Yang Ren, Xinwei Yang, Lingtao Ding, Dongfang Liu, Yong Tao, Jianzhong Huang, Chongrong Ke   +6 more
doaj   +1 more source

PQQ Dietary Supplementation Prevents Alkylating Agent-Induced Ovarian Dysfunction in Mice

Frontiers in Endocrinology, 2022
Alkylating agents (AAs) that are commonly used for cancer therapy cause great damage to the ovary. Pyrroloquinoline-quinine (PQQ), which was initially identified as a redox cofactor for bacterial dehydrogenases, has been demonstrated to benefit the ...
Xiuliang Dai, Xiangjiao Yi, Yufeng Wang, Wei Xia, Jianguo Tao, Jianguo Tao, Jun Wu, Dengshun Miao, Li Chen   +8 more
doaj   +1 more source

Draft Genome Sequences of Two Gammaproteobacterial Methanotrophs Isolated from Rice Ecosystems [PDF]

, 2017
The genomes of the aerobic methanotrophs “Methyloterricola oryzae” strain 73aT and Methylomagnum ishizawai strain 175 were sequenced. Both strains were isolated from rice plants.
Bringel, Françoise, DiSpirito, Alan A., Dunfield, Peter F., Frindte, Katharina, Jetten, Mike S. M., Kalyuzhnaya, Marina G., Khmelenina, Valentina N., Klotz, Martin G., Knief, Claudia, Murrell, J. Colin, Op den Camp, Huub J. M., Sakai, Yasuyoshi, Semrau, Jeremy D., Shapiro, Nicole, Stein, Lisa Y., Svenning, Mette M., Trotsenko, Yuri A., Vuilleumier, Stéphane, Woyke, Tanja   +18 more
core   +11 more sources

Mineral Phosphate Solubilization in Burkholderia tropica Involves an Inducible PQQ-Glucose Dehydrogenase [PDF]

, 2016
Aims: The objective of this work was to provide knowledgement about the mechanism and regulation of the mineral phosphate solubilization in Burkholderia. tropica. To this end, the expression of the direct extracellular oxidative pathway in B. tropica was
Bernabeu, Pamela Romina, Boiardi, Jose Luis, Galar, Maria Lina, Garcia Ferreyra, Gimena, Garcia, Sabrina Soledad, Guidi, Verónica Inés, Luna, Maria Flavia   +6 more
core   +2 more sources

Methylobacterium sp. 2A is a plant growth-promoting rhizobacteria that has the potential to improve potato crop yield under adverse conditions [PDF]

, 2020
A Gram-negative pink-pigmented bacillus (named 2A) was isolated from Solanum tuberosum L. cv. Desirée plants that were strikingly more developed, presented increased root hair density, and higher biomass than other potato lines of the same age.
Fantino, Elisa Inés, Fernández Do Porto, Darío Augusto, Grossi, Cecilia Eugenia María, Serral, Federico, Ulloa, Rita Maria, Zawoznik, Myriam Sara   +5 more
core   +1 more source