Results 81 to 90 of about 94,951 (115)

A Novel Genetic Engineering Approach for DON Detoxification Using a Yeast-Based Multi-Enzyme System

Biology
Deoxynivalenol (DON), a Group III carcinogenic mycotoxin frequently detected in cereals and animal-derived food products, poses serious health risks to animals and humans.
Rong Li, Jia Song, Bo Sun, Aike Li, Shiqi Zou, Ming Liu, Linshu Jiang, Jingjing Shi, Qingming Cao, Chen Zhao, Weiwei Wang   +10 more
doaj   +1 more source

Methods for Expression, Purification, and Characterization of PqqE, a Radical SAM Enzyme in the PQQ Biosynthetic Pathway

Methods in Enzymology, 2018
PqqE is the first enzyme in the biosynthetic pathway of the redox cofactor pyrroloquinoline quinone (PQQ), catalyzing the formation of a carbon–carbon bond in the precursor peptide PqqA.
Wen Zhu, A. M. Martins, J. Klinman
semanticscholar   +1 more source

Unveiling the Broad Substrate Specificity of Deoxynivalenol Oxidation Enzyme DepA and Its Role in Detoxifying Trichothecene Mycotoxins

Toxins
DepA, a pyrroloquinoline quinone (PQQ)-dependent enzyme isolated from Devosia mutans 17-2-E-8, exhibits versatility in oxidizing deoxynivalenol (DON) and its derivatives.
Yan Zhu, Edicon Tze Shun Chan, Nadine Abraham, Xiu-Zhen Li, Weijun Wang, Lili Mats, Honghui Zhu, Jason Carere, Ting Zhou   +8 more
doaj   +1 more source

A Metal–Organic Hybrid Composed of Dual Quenching Cofactors as a Nanoquencher for the Fluorescent Determination of Protease Caspase-3

Biosensors
Nanoquenchers with a single quenching cofactor exhibit limited fluorescence quenching efficiency. In this work, a metal–organic hybrid with dual quenching cofactors (Cu2+ and pyrroloquinoline quinone or PQQ) was prepared by metal-coordinated assembly and
Fengli Gao, Lin Liu, Cancan He, Yong Chang, Weiqiang Wang   +4 more
doaj   +1 more source

Growth and gene expression of Pseudomonas nitroreducens TX1 on octylphenol polyethoxylate surfactants

Applied Microbiology and Biotechnology
Pseudomonas nitroreducens ATCC PTA-6168 (also named TX1) efficiently grows on non-ionic surfactants as the sole source of carbon and energy aerobically.
Lam Dinh Bui, Po-Chun Tsai, Tuan Ngoc Nguyen, Chih-Chen Chen, Shir-Ly Huang   +4 more
doaj   +1 more source

Eliciting Clavulanic Acid Biosynthesis: The Impact of Bacillus velezensis FZB42 on the Metabolism of Streptoyces clavuligerus ATCC 27064

Metabolites
Background/Objectives: Clavulanic acid (CA) is produced by cell suspension cultures of Streptomyces clavuligerus ATCC 27064, and is widely used as a beta-lactamase inhibitor to combat antibiotic resistance.
Luisa F. Patiño, Carlos Caicedo-Montoya, Laura Pinilla-Mendoza, Jaison H. Cuartas, Rigoberto Ríos-Estepa   +4 more
doaj   +1 more source

Characteristic Reaction Mode of Cofactor PQQ toward Nucleophiles

Characteristic Reaction Mode of Cofactor PQQ toward Nucleophiles
[Abstract] The characteristic reaction mode of coenzyme PQQ toward nucleophiles such as alcohols, amines, and hydrazines are surveyed. The selectivity of addition position of nucleophiles to the carbonyl group of PQQ was affected by reaction conditions and substituents of nucleophiles. Reaction mechanisms were discussed.
openaire  

The Quinoid Cofactors, Pyrroloquinoline Quinone (PQQ), Topaquinone (TPQ) and Tryptophan Tryptophylquinone (TTQ)

Journal of Nutritional Science and Vitaminology, 1992
openaire   +3 more sources

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Substituted Quinoline Quinones as Surrogates for the PQQ Cofactor: An Electrochemical and Computational Study

Organic Letters, 2015
Pyrroloquinoline quinones (PQQ) are important cofactors that shuttle redox equivalents in diverse metalloproteins. Quinoline 7,8-quinones have been synthesized and characterized as surrogates for PQQ to elucidate redox energetics within metalloenzyme active sites.
Patrick Carroll, Eric Schelter
exaly   +4 more sources

C-4 and C-5 adducts of cofactor PQQ (pyrroloquinolinequinone). Model studies directed toward the action of quinoprotein methanol dehydrogenase

Journal of the American Chemical Society, 1993
Methanol addition to the trimethyl ester of cofactor PQQ (PQQTME) was investigated in detail to obtain information on the action of quinoprotein methanol dehydrogenase. The hemiacetal-type adduct was easily isolated from a methanol solution of PQQTME.
Tsuyoshi Inoue, Shinobu Itoh, Yoshiki Ohshiro   +2 more
exaly   +3 more sources