Results 91 to 100 of about 13,975 (182)

Prion Seeding Activity in Plant Tissues Detected by RT-QuIC

Pathogens
Prion diseases such as scrapie, bovine spongiform encephalopathy (BSE), and chronic wasting disease (CWD) affect domesticated and wild herbivorous mammals. Animals afflicted with CWD, the transmissible spongiform encephalopathy of cervids (deer, elk, and
Kate Burgener, Stuart Siegfried Lichtenberg, Daniel P. Walsh, Heather N. Inzalaco, Aaron Lomax, Joel A. Pedersen   +5 more
doaj   +1 more source

The Role of the Simulation in Supporting Newly Graduated Nurses in Their First 5 Months of Working Transition: Findings From a Mixed‐Method Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To understand the role of simulation in ensuring the development of the competencies expected by newly graduated register nurses (NGRNs) from the work initiation up to 5 months of transition. Methods Mixed‐method study design. A longitudinal phase employing the Nurse Competence Scale (NCS, from 0 to 100, excellent) to assess the perceived
Maura Mesaglio, Sara Dentice, Luca Grassetti, Illarj Achil, Anna Bernardinis, Davide Caruzzo, Anna Inserra, Irene Mansutti, Elisa Mattiussi, Sandra Menegoz, Tommaso Piani, Elena Vanzo, Stefania Chiappinotto, Alvisa Palese   +13 more
wiley   +1 more source

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease.

PLoS Pathogens
Prion diseases uniquely manifest in three distinct forms: inherited, sporadic, and infectious. Wild-type prions are responsible for the sporadic and infectious versions, while mutant prions cause inherited variants like fatal familial insomnia (FFI) and ...
Daniel J Walsh, Judy R Rees, Surabhi Mehra, Matthew E C Bourkas, Lech Kaczmarczyk, Erica Stuart, Walker S Jackson, Joel C Watts, Surachai Supattapone   +8 more
doaj   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

Tick‐borne diseases in subtropical dairy farming: The role of calf rearing strategies in antibody and antigen prevalence Enfermedades Transmitidas por Garrapatas en la Ganadería Lechera subtropical: El Papel de las Estrategias de Crianza de Terneros en la Prevalencia de Anticuerpos y Antígenos

Medical and Veterinary Entomology, EarlyView.
Tropical farmers try to adapt calf‐rearing systems to temperate dairy industry standards. Calves in tick‐infested areas develop stronger immunity to TBD under controlled exposure to ticks. Early tick exposure promotes sustainable management, balancing tick infestation and developing TBD immunity.
Daniela Balseca, Valeria Paucar‐Quishpe, Richar Rodríguez‐Hidalgo, Ximena Pérez‐Otáñez, Darío Cepeda‐Bastidas, Cecilia Pérez‐Escalante, María‐Augusta Chávez‐Larrea, Sandra Enríquez, Jorge Grijalva, Sophie O. Vanwambeke, Claude Saegerman, Lenin Ron‐Garrido   +11 more
wiley   +1 more source

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Science Attitudes: Enjoyment of Science Lessons and Interest in Pursuing a Scientific Career. High School Students' Gender Differences

School Science and Mathematics, EarlyView.
ABSTRACT In this study, the dimensions of enjoying science lessons and pursuing science careers were examined under gender considerations. Ex post facto research was conducted on high school students (N = 599) from the Canary Islands who completed a Spanish version of the Test of Science Related Attitudes (TORSA).
Luis Miguel Rivera‐Gavidia, Juan José Marrero‐Galván   +1 more
wiley   +1 more source

Inhibition and Formation of Amyloid Fibrils in the Bulk and at the Interface of Biomolecular Condensates

Angewandte Chemie, Volume 138, Issue 33, 10 August 2026.
In this review, we discuss how biomolecular condensates can inhibit amyloid aggregation in their interior, while still facilitating fibril formation at the interface between the dense and dilute phases, where molecular and mesoscale properties are likely optimal to promote protein aggregation.
Marcell Papp, Chiara Morelli, Sarah Khawaja, Paolo Arosio   +3 more
wiley   +2 more sources

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source