Results 151 to 160 of about 13,975 (182)

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness. [PDF]

Acta Neuropathol Commun
Eraña H, Vidal E, Fernández-Borges N, Charco JM, Díaz-Domínguez CM, Sampedro-Torres-Quevedo C, San-Juan-Ansoleaga M, Fernández-Muñoz E, Galarza-Ahumada J, Pérez-Castro MÁ, Gonçalves-Anjo N, Piñeiro P, Pirisinu L, Di Bari MA, Giler S, Raimondi I, Espinosa JC, Vanni I, D'Agostino C, Rodríguez-Cuesta J, Pasetto L, Bonetto V, González-Martín N, Teijeira S, Zou WQ, Geijo M, Torres JM, Chiesa R, Sánchez-Martín MA, Nonno R, Requena JR, Castilla J.   +31 more
europepmc   +1 more source

Overlap of nonbreeding wandering albatrosses with fisheries and implications for colony‐specific population trajectories at South Georgia

Conservation Biology, Volume 40, Issue 4, August 2026.
Abstract Bycatch in fisheries is one of the most serious threats to pelagic seabirds, causing major population declines. Mitigation measures can reduce bycatch substantially, but many fisheries fail to apply best practices, and seabird mortality remains high.
V. Warwick‐Evans, E. J. Pearmain, R. A. Phillips   +2 more
wiley   +1 more source

Oligosaccharyltransferase (OST) complex inhibition effectively treats rodent and human prions. [PDF]

PLoS Pathog
Beauchemin KS, Kun J, Groveman B, Williams K, Salerno F, Francomacaro LM, Robison P, Haigh CL, Supattapone S.   +8 more
europepmc   +1 more source

Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration

Journal of Neurochemistry, Volume 170, Issue 8, August 2026.
Graphical illustration of the microtubule interactome following spinal cord injury as potential targets for therapy. ABSTRACT Spinal cord injury (SCI) triggers an immediate and sustained disruption of the composition and organization of the neuronal cytoskeleton.
Itzhak Fischer, Peter W. Baas
wiley   +1 more source

Modeling chronic wasting disease transmission risk in mule deer related to habitat characteristics. [PDF]

PLoS One
Christensen EM, Kleist NJ, Edmunds DR, Heinrichs JA, Saher DJ, Whipple AL, DeVivo M, Aldridge CL.   +7 more
europepmc   +1 more source

Recombinant Human Collagen in Clinical Medicine

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Background Collagen is the dominant structural protein of vertebrate connective tissues and a central biomaterial in skin, cornea, tendon, cartilage, bone, vessel, oral mucosa, and wound repair. Traditional collagen products have largely been extracted from bovine, porcine, fish, or other animal tissues.
Kyu‐Ho Yi, Jong Keun Song, Hongseok Kim   +2 more
wiley   +1 more source

Involvement of the spleen in the anti-prion activity of hydroxypropyl methylcellulose in mice. [PDF]

Sci Rep
Teruya K, Oguma A, Nishizawa K, Doh-Ura K.   +3 more
europepmc   +1 more source

Structural Heterogeneity of TDP‐43 Fragments in Alzheimer's Disease and Primary Age‐Related Tauopathy by Artificial Intelligence (AI)–Based 3D Segmentation

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
Immunostaining of anti‐phosphorylated TDP‐43 (pTDP‐43), TDP‐43 C‐terminal fragment (TDP‐43 C) and TDP‐43 N‐terminal fragment (TDP‐N), combined with an AI‐based object recognition, reconstruction and automatic 3D morphometric analysis pipeline in limbic regions revealed that distinct TDP‐43 fragment aggregation patterns, underscoring region‐specific ...
Gokhan Uruk, Rodolfo G. Gatto, Nadia Hossain, Jennifer L. Whitwell, R. Ross Reichard, Keith A. Josephs   +5 more
wiley   +1 more source

Silent Propagation of Classical Scrapie Prions in Homozygous K₂₂₂ Transgenic Mice. [PDF]

Emerg Infect Dis
Fernández-Borges N, Marín-Moreno A, Espinosa JC, Canoyra S, Andréoletti O, Torres JM.   +5 more
europepmc   +1 more source

Transgenic A53T Mice Have Astrocytic α‐Synuclein Aggregates in Dopamine and Striatal Regions

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
To identify whether astrocytes accumulate α‐synuclein aggregates before or after neurons, astrocytes from the midbrain and striatum of M83 A53T transgenic mice were compared to wild‐type. The substantia nigra pars compacta had more astrocytes than the ventral tegmental area or striatum, and small α‐synuclein aggregates were observed even within wild ...
Cormac Peat, Asheeta Prasad, David I. Finkelstein, Caroline Sue, Jennifer A. Johnston, Clare L. Parish, Lachlan Thompson, Deniz Kirik, Glenda M. Halliday   +8 more
wiley   +1 more source