Results 61 to 70 of about 1,017,616 (266)
Representing space for practical reasoning [PDF]
, 1987 This paper describes a new approach to representing space and time for practical reasoning, based on space-filling cells. Unlike R n, the new models can represent a bounded region of space using only finitely many cells, so they can be manipulated ...
Margaret M. Fleck
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Chiral Casimir Forces: Repulsive, Enhanced, Tunable [PDF]
, 2018 Both theoretical interest and practical significance attach to the sign and strength of Casimir forces. A famous, discouraging no-go theorem states that "The Casimir force between two bodies with reflection symmetry is always attractive." Here we ...
Jiang, Qing-Dong, Wilczek, Frank
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Should We Be Convicting People We Don't Believe to Be Guilty?
Quaestio FactiIt is doubtful that knowledge of guilt is a necessary condition for a criminal conviction. More plausibly, justified belief is required. But a criminal conviction is not grounded in belief as straightforwardly as is sometimes assumed. While epistemology
Hock Lai Ho
doaj +1 more source
Teoria Jurídica Contemporânea, 2016 Resumen: El presente paper analiza la contribución de Edna Ullmann-Margalit al desarrollo del concepto filosófico de presunción (asumir desde la ocurrencia de un hecho conocido la ocurrencia de un hecho no conocido a modo de actuar sobre él).
Janaina Matida
doaj +1 more source
Theorising and practitioners in HRD: the role of abductive reasoning [PDF]
, 2011 Purpose – The purpose of this paper is to argue that abductive reasoning is a typical but usually unrecognised process used by HRD scholars and practitioners alike.
Gold, J
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Proprietary Reasons and Joint Action [PDF]
Some of the reasons one acts on in joint action are shared with fellow participants. But others are proprietary: reasons of one’s own that have no direct practical significance for other participants.
A Roth +16 more
core +1 more source