Results 91 to 100 of about 1,616,974 (288)

Pragmatic awareness of conversational implicatures and the usefulness of explicit instruction

Revista Nebrija de Linguistica Aplicada a la Enseñanza de Lenguas, 2015
The present study attempts to investigate the degree of pragmatic awareness of learners of English as a foreing language and also whether explicit instruction facilitates the learners’ interpretation of these implicatures.
Luciana María Cignetti, María Salomé Di Giuseppe   +1 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Rendering the German modal particle denn in Turkish: a translation-oriented analysis of literary texts

Frontiers in Language Sciences
IntroductionGerman modal particles pose a major challenge for translation because their meanings are primarily discourse-pragmatic, interactional, and context-dependent rather than lexical or propositional.
Salih Özenici, Kemal Demir
doaj   +1 more source

Pragmatic awareness of Suggestions: From (Im)Polite Mannerism to Attitudinal Appropriateness [PDF]

Research in English Language Pedagogy, 2017
The present research seeks to determine: (a) Iranian EFL learners’ application of suggestion semantic formulae ;(b) their attitude of appropriateness in terms of confidence in the employment of appropriate supportive moves; (c), their (im)polite ...
Hamid Allami, Nasim Boustani
doaj  

Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution

Advanced Science, EarlyView.
MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge, Xiangyang Ma, Jiyan Li, Mengxiang Wang, Fuping Lu, Yihan Liu, Lin Wang   +6 more
wiley   +1 more source

Cross – Cultural Pragmatic Failure

Revue des Sciences Humaines, 2014
Successful communication in a second language needs both, the linguistic and the pragmatic competences of that language. But the common mistake second language learners make is that they rely more on linguistic knowledge rather than communication.
Fahima NOUICHI
doaj  

Evaluating India’s Position in Pragmatic Clinical Trial for Public Healthcare: A Key to Real World Healthcare Solutions

National Journal of Community Medicine
Pragmatic Clinical Trials (PCTs) are valuable tools for evaluating interventions in real-world settings, providing insights for clinical practice.
Smruti Besekar, Sangita Jogdand, Satyawan Singh Patel   +2 more
doaj   +1 more source

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci, Giulia Maesano, Leonardo Casini, Maurizio Canavari, Marija Cerjak   +4 more
wiley   +1 more source

Extension Economists: Valued in Mission, Penalized in Practice

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT As the public engagement arm of the land‐grant mission, we argue that Extension faculty in US agricultural economics departments face an identity crossroads as they struggle for institutional support. Specifically, we argue that Extension economists function as boundary‐spanning professionals within academic structures that often devalue ...
Trey Malone, Craig W. Carpenter, Courtney Bir, Andrew J. Van Leuven, Rebecca Wasserman‐Olin, Wendong Zhang   +5 more
wiley   +1 more source