Results 101 to 110 of about 6,158,274 (301)

Research Report 2012 [PDF]

, 2013
The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, undertakes research with national and international trial groups, and contributes expertise to trials run by others.
NHMRC Clinical Trials Centre
core  

Using a business model approach and marketing techniques for recruitment to clinical trials [PDF]

, 2011
Peer ...
Knight Rosemary, Campbell, Marion K., Rosemary Knight, Shakur Haleema, Treweek Shaun, Shaun Treweek, Haleema Shakur, Knight, Rosemary, Alison M McDonald, Chris Speed, Free Caroline, Free, Caroline, Caroline Free, Marion K Campbell, McDonald, Alison M., Speed Chris, Speed, Chris, McDonald Alison M, Treweek, Shaun Patrick, Shakur, Haleema, McDonald, Alison M, Campbell Marion K, Treweek, Shaun, Campbell, Marion K   +23 more
core   +2 more sources

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Research Report 2006–2007 [PDF]

, 2008
The National Health and Medical Research Council Clinical Trials Centre conducts its own clinical trials, provides expertise and infrastructure for trials run by other groups, and undertakes research aiming to improve both the conduct of trials and the ...
NHMRC Clinical Trials Centre
core  

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

Pragmatic clinical trials and the consent process

Research Ethics Review, 2018
Pragmatic clinical trials (PCTs) are a relatively new methodological approach to the execution of clinical research that can increase research efficiency and provide access to unique data.
Blake Murdoch, Timothy Caulfield
doaj   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

What is the impact on recruitment of a shortened compared with a standard-length participant information leaflet? PROMETHEUS in IBD-BOOST: study within a trial, a decentralised UK randomised controlled trial

Trials
Background Participant Information Leaflets (PILs) are lengthy and increasingly complex, and could deter research participation. A shortened PIL may be more appealing as it is likely to provide a more a manageable volume of information. Previous research
L. Miller, A. Hart, F. Cléirigh-Büttner, C. Arundel, T. Hamborg, S. McGuinness, R. Moss-Morris, A. Parker, C. Relton, I. Stagg, L. Sweeney, V. Wileman, Z. Zenasni, C. Norton   +13 more
doaj   +1 more source

Effectiveness of high-dose versus standard-dose influenza vaccines against hospitalisation according to frailty risk: a prespecified analysis of the randomised trial DANFLU-2

The Lancet. Healthy Longevity
Summary: Background: Frailty is a major risk factor for influenza-related complications and can influence vaccine effectiveness. We aimed to assess the relative vaccine effectiveness (rVE) of high-dose (HD-IIV) versus standard-dose inactivated influenza ...
Caroline Espersen, MD, Niklas D Johansen, MD PhD, Daniel Modin, MD, Kira H Janstrup, MSc PhD, Matthew M Loiacono, PhD, Rebecca C Harris, MSc PhD, Youjun Huang, PhD, Carsten S Larsen, MD DMSc, Lykke Larsen, MD PhD, Lothar Wiese, MD PhD, Michael Dalager-Pedersen, MD PhD, Brian L Claggett, PhD, Katja V Bartholdy, MD, Katrine F Bernholm, MD, Julie I-M H Borchsenius, MD, Filip S Davidovski, MD, Lise W Davodian, MD, Maria Dons, MD PhD, Lisa S Duus, MD, Frederik H Fussing, MD, Anne Marie R Jensen, MD, Nino E Landler, MD PhD, Adam C F Langhoff, MD, Mats C H Lassen, MD PhD, Anne B Nielsen, MD, Camilla I Ottosen, MD, Morten Sengeløv, MD PhD, Kristoffer G Skaarup, MD, Scott D Solomon, Prof, Martin J Landray, Prof, Gunnar H Gislason, Prof, Lars Køber, Prof, Pradeesh Sivapalan, MD PhD, Cyril J-M Martel, PhD, Jens U S Jensen, Prof, Kazumasa Harada, MD PhD, Gaetan Gavazzi, Prof, Tor Biering-Sørensen, Prof   +37 more
doaj   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source