Results 141 to 150 of about 71,888 (256)

Considering user experience and cognitive load in the design and development of a virtual reality application for embodied anatomy learning

Anatomical Sciences Education, EarlyView.
Abstract Virtual reality (VR) offers new possibilities for anatomy education through immersive and embodied interaction. Early‐stage evaluation of VR tools is necessary to assess user experience and perceived cognitive load and to guide iterative development.
Mélanie Gallot, Mira Hajj‐Hassan, Rawad Chaker, Christian Collet, Nady Hoyek   +4 more
wiley   +1 more source

The importance of patient-reported outcomes in pragmatic clinical trials. [PDF]

J Natl Cancer Inst, 2023
Jim HSL, Brady-Nicholls R, Hershman DL.
europepmc   +1 more source

Collection of implementation-related data in pragmatic clinical trials: a cross-sectional study from the NIH Pragmatic Trials Collaboratory. [PDF]

Implement Sci Commun
Trinkley KE, Gohil S, Salsbury SA, Burgess DJ, Doorenbos AZ, Mittman BS, Norton WE, Bosworth HB, Staman KL, Check D.   +9 more
europepmc   +1 more source

Distinguishing Clinical and Research Risks in Pragmatic Clinical Trials: The Need for Further Stakeholder Engagement. [PDF]

Am J Bioeth, 2023
Wilfond BS, Toraman Turk S, Kraft SA, Weiss EM, Tarr PI, Schnadower D, Freedman SB.   +6 more
europepmc   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Pragmatic Clinical Trials: A Study Design for Real-World Evidence. [PDF]

Am J Nurs
Capili B, Anastasi JK.
europepmc   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Do Clinicians Have a Duty to Participate in Pragmatic Clinical Trials? [PDF]

Am J Bioeth, 2023
Garland A, Morain S, Sugarman J.
europepmc   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

A framework for health systems to assess and prioritize participation in pragmatic clinical trials. [PDF]

Learn Health Syst
Morain SR, Semler MW, Casey JD.
europepmc   +1 more source