Results 91 to 100 of about 12,380 (194)

Development and validation of the discriminating method of prasugrel dissolution in tablets using ultraviolet detection

open access: yesActa Scientiarum. Health Sciences, 2014
Current study develops and validates a dissolution test for Prasugrel hydrochloride 10 mg in coated tablets. After sink condition, filters and drug stability were evaluated, the discriminatory dissolution conditions were achieved with a USP apparatus 1 ...
Camila Rigobello   +2 more
doaj   +1 more source

Vollblutaggregometrische Untersuchungen zur Thrombozytenfunktionshemmung von Prasugrel verglichen mit Clopidogrel und Korrelation von Prasugrel Low-Respondern mit CYP2B6 und CYP2C9 Polymorphismen

open access: yes, 2015
Insgesamt 355 Patienten wurden unter antithrombozytärer Therapie mittels Impedanzaggregometrie auf das Vorliegen von Low-Response untersucht. Als Agonist dienten hierbei Arachidonsäure und ADP.
Franken, Cora Christina
core  

Impact of Intravenous Lysine Acetylsalicylate Versus Oral Aspirin on Prasugrel-Inhibited Platelets: Results of a Prospective, Randomized, Crossover Study (the ECCLIPSE Trial)

open access: yes, 2015
Ensayo clínico unicéntrico abierto y cruzado donde se evaluó el efecto en voluntarios sanos sobre la función plaquetaria en función de la administración intravenosa de acetilsalicilato de lisina o aspirina oral.
Macaya Miguel, Carlos   +9 more
core   +1 more source

Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes

open access: yes, 2019
Background The relative merits of ticagrelor as compared with prasugrel in patients with acute coronary syndromes for whom invasive evaluation is planned are uncertain.
Schüpke, Stefanie   +41 more
core   +1 more source

Pharmacokinetics and pharmacodynamics of prasugrel in healthy Japanese subjects

open access: yes, 2016
This randomized double-blind and placebo-controlled study assessed the pharmacodynamics and pharmacokinetics of prasugrel in healthy adult Japanese male subjects after single (n = 50) and multiple (n = 40) oral administration.
Ikeda, Yasuhiko   +5 more
core   +1 more source

Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel

open access: yes, 2019
The value of platelet function testing (PFT) in predicting clinical outcomes and guiding P2Y12-inhibitor treatment is uncertain. In a pre-specified sub-study of the TROPICAL-ACS trial, we assessed ischaemic and bleeding risks according to high platelet ...
Ruzsa Zoltán   +14 more
core   +1 more source

Clopidogrel, ticagrelor, prasugrel or an alternation of two P2Y12 in patients with acute myocardial infarction with cardiogenic shock

open access: yesFrontiers in Cardiovascular Medicine
BackgroundData are lacking on the effects of the alternation of P2Y12 receptor antagonists (P2Y12) on bleeding and outcome in patients with myocardial infarction (MI) with cardiogenic shock (CS). We compared the effects of different P2Y12 and alternation
Vojko Kanic, Gregor Kompara
doaj   +1 more source

Evaluation of recombinant factor VIIa, tranexamic acid and desmopressin to reduce prasugrel-related bleeding

open access: yes, 2018
BACKGROUND: Prasugrel is a thienopyridine that inhibits platelet aggregation more rapidly and effectively than clopidogrel, with an increased bleeding risk.
Fanny Bonhomme   +9 more
core   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

In silico Investigation on Clopidogrel, Prasugrel and Ticagrelor as Potential Mono Antiplatelet Therapy for Acute Coronary Syndrome

open access: yesMCBS (Molecular and Cellular Biomedical Sciences)
Background: In acute coronary syndrome (ACS), antiplatelet therapy is crucial for inhibiting platelet aggregation. Dual antiplatelet therapy (DAPT) commonly employs aspirin along with clopidogrel, prasugrel, or ticagrelor. This is well known that aspirin
Muhammad Naufal Hibatullah   +2 more
doaj   +1 more source

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