Results 51 to 60 of about 9,741 (153)

Multi‐Modality Imaging Evaluation and Optimal Management of Complex Coronary Artery Aneurysms

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Coronary artery aneurysms (CAA) present variably and require multimodal imaging—catheterization, CTCA, stress echocardiography among others—for diagnosis. Management, individualized per patient, includes medical, percutaneous, or surgical approaches.
Aro Daniela Arockiam, Sharmeen Sorathia, Rishabh Khurana, Ankit Agrawal, Elio Haroun, Alexandra Hall, Christine Jellis, Shinya Unai, Tom Kai Ming Wang   +8 more
wiley   +1 more source

Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: a double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels

Cardiovascular Diabetology, 2020
Background Despite increased atherothrombotic risk in type 2 diabetes mellitus, (T2DM) the best preventative antithrombotic strategy remains undetermined. We defined the effects of three antiplatelet agents on functional readout and biomarker kinetics in
William A. E. Parker, Christian Schulte, Temo Barwari, Fladia Phoenix, Sam M. Pearson, Manuel Mayr, Peter J. Grant, Robert F. Storey, Ramzi A. Ajjan   +8 more
doaj   +1 more source

Viscoelastic Testing for Coagulation Management in Vascular Surgery—A Narrative Review

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Viscoelastic testing (VET) has been increasingly used in cardiac, trauma, and hepatic surgery where it helps tackle the development of complex coagulopathies. Despite this, data on using VETs in vascular surgery remains limited to small and non‐randomised control studies. Although the improvement in vascular techniques has decreased
Alexandru Munteanu, Elena Bax
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Absence of differential effect of ticagrelor versus prasugrel maintenance dose on endothelial function in patients with stable coronary artery disease

Hellenic Journal of Cardiology, 2018
Background: Endothelial function may be improved by ticagrelor through adenosine-mediated mechanisms. We aimed to assess the effect of ticagrelor versus prasugrel on endothelial function in patients with stable coronary artery disease (CAD).
Ioanna Xanthopoulou, Ilianna Bei, Theodora Bampouri, Nikolaos Barampoutis, Athanasios Moulias, Periklis Davlouros, Dimitrios Alexopoulos   +6 more
doaj   +1 more source

A Framework to Quantify Disparities in Pharmacogenomic Treatment Concordance and Drug Response Outcomes

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Clinical PGx practice guidelines (PGx guidelines) may have limited generalizability for “marginalized” groups. We proposed the five‐step Real‐World Data for Genome‐Guided Prescribing (ReGGRx) framework and, using All of Us research program (AoU) data, examined its ability to estimate disparities in concordance with and benefit from PGx ...
Ilia Rattsev, James M. Stevenson, Casey Overby Taylor   +2 more
wiley   +1 more source

The risk of dyspnea in patients treated with third-generation P2Y12 inhibitors compared with clopidogrel: a meta-analysis of randomized controlled trials

BMC Cardiovascular Disorders, 2020
Background Ticagrelor and prasugrel are two third-generation oral P2Y12 inhibitors which are more commonly used in clinical practice. However, dyspnea has been consecutively reported in patients using third-generation oral P2Y12 inhibitors.
Na Zhang, Weisen Xu, Ou Li, Bing Zhang
doaj   +1 more source

National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025

Medical Journal of Australia, Volume 224, Issue 2, February 2026.
ABSTRACT Introduction The Australian clinical guideline for diagnosing and managing acute coronary syndromes 2025 establishes a new clinical standard for the diagnosis and management of acute coronary syndromes (ACS) in Australia. The new guideline replaces the 2016 guideline, representing the first major update in nearly a decade.
David B. Brieger, Louise A. Cullen, Tom G. Briffa, Sarah Zaman, Ian A. Scott, Cynthia Papendick, Elaine Ho, Victoria Leitch, Dannii Dougherty, Garry Jennings   +9 more
wiley   +1 more source

Place of Prasugrel, P2Y12 receptor antagonist, in an early invasive treatment of patients with acute coronary syndrome (according to the results of multicenter randomized controlled trial ISAR-REACT 5)

Российский кардиологический журнал, 2019
The conclusion of the Expert Council reports an agreement on the place of the P2Y12 receptor blocker prasugrel in the early invasive treatment of patients with acute coronary syndrome ACS, according to the results of the multicenter randomized controlled
S. N. Tereshchenko, M. G. Glezer, S. A. Abugov, O. V. Averkov, S. I. Antipov, A. S. Galyavich, M. Yu. Gilyarov, D. V. Duplyakov, A. A. Efremushkina, D. A. Zateyshchikov, V. V. Ivanenko, E. D. Kosmacheva, O. V. Krestyaninov, Yu. M. Lopatin, E. P. Panchenko, V. V. Ryabov, E. V. Samokhvalov, I. I. Staroverov, S. A. Ustyugov, A. V. Khripun, S. V. Shalaev, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. S. Yakushin   +24 more
doaj   +1 more source

Migraine and patent foramen ovale: correlation, coexistence, dependence. A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 1, Page 307-321, January 2026.
Plain Language Summary This review looked at what scientists know about the connection between migraine and a small heart opening called a patent foramen ovale (PFO). It showed that people with migraine, especially with aura, often have PFO, but it is not certain whether closing this heart opening helps prevent strokes in these patients.
Olga Grodzka, Michał Borończyk, Anna Zduńska, Julia Węgrzynek‐Gallina, Izabela Domitrz, Anetta Lasek‐Bal   +5 more
wiley   +1 more source