Results 61 to 70 of about 9,741 (153)

Comparison of P2Y12 inhibitors for mortality and stent thrombosis in patients with acute coronary syndromes: Single center study of 10 793 consecutive ‘real-world’ patients

open access: yesPlatelets, 2017
Three oral platelet P2Y12 inhibitors, clopidogrel, prasugrel, and ticagrelor, are available for reducing the risk of cardiovascular death and stent thrombosis in patients with acute coronary syndromes (ACS).
Rebecca Gosling   +7 more
doaj   +1 more source

Comparison of prasugrel and clopidogrel in patients with acute coronary syndrome undergoing percutaneous coronary intervention

open access: yesVascular Health and Risk Management, 2009
Nicholas B Norgard,1 Mazen Abu-Fadel21University at Buffalo, School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY, USA; 2University of Oklahoma Health Sciences Center, Cardiovascular Section, Oklahoma City, OK, USAAbstract: Antiplatelet agents are
Nicholas B Norgard, Mazen Abu-Fadel
doaj  

Prasugrel Results in Higher Decrease in High-Sensitivity C-Reactive Protein Level in Patients Undergoing Percutaneous Coronary Intervention Comparing to Clopidogrel

open access: yesClinical Medicine Insights: Cardiology, 2016
Objectives A growing body of clinical and laboratory evidence indicates that inflammation plays a crucial role in atherosclerosis. In the present study, we compared the effects of clopidogrel and prasugrel on high-sensitivity C-reactive protein (hs-CRP ...
Shokoufeh Hajsadeghi   +9 more
doaj   +1 more source

Post percutaneous coronary interventional adverse cardiovascular outcomes and bleeding events observed with prasugrel versus clopidogrel: direct comparison through a meta-analysis

open access: yesBMC Cardiovascular Disorders, 2018
Background Due to limitations associated with clopidogrel following percutaneous coronary intervention (PCI), other newer oral anti-platelet agents are being studied.
Pravesh Kumar Bundhun, Feng Huang
doaj   +1 more source

Real-world comparison of clopidogrel, prasugrel and ticagrelor in patients undergoing primary percutaneous coronary intervention

open access: yesOpen Heart, 2019
Background There is a paucity of real-world outcome data comparing clopidogrel, prasugrel and ticagrelor in primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
Jim McLenachan   +12 more
doaj   +1 more source

Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Over the past decade, major society guidelines have recommended the use of newer P2Y12 inhibitors over clopidogrel for those undergoing percutaneous coronary intervention for acute coronary syndrome.
Mohamed O. Mohamed   +9 more
doaj   +1 more source

Development and validation of the discriminating method of prasugrel dissolution in tablets using ultraviolet detection

open access: yesActa Scientiarum. Health Sciences, 2014
Current study develops and validates a dissolution test for Prasugrel hydrochloride 10 mg in coated tablets. After sink condition, filters and drug stability were evaluated, the discriminatory dissolution conditions were achieved with a USP apparatus 1 ...
Camila Rigobello   +2 more
doaj   +1 more source

Clopidogrel, ticagrelor, prasugrel or an alternation of two P2Y12 in patients with acute myocardial infarction with cardiogenic shock

open access: yesFrontiers in Cardiovascular Medicine
BackgroundData are lacking on the effects of the alternation of P2Y12 receptor antagonists (P2Y12) on bleeding and outcome in patients with myocardial infarction (MI) with cardiogenic shock (CS). We compared the effects of different P2Y12 and alternation
Vojko Kanic, Gregor Kompara
doaj   +1 more source

In silico Investigation on Clopidogrel, Prasugrel and Ticagrelor as Potential Mono Antiplatelet Therapy for Acute Coronary Syndrome

open access: yesMCBS (Molecular and Cellular Biomedical Sciences)
Background: In acute coronary syndrome (ACS), antiplatelet therapy is crucial for inhibiting platelet aggregation. Dual antiplatelet therapy (DAPT) commonly employs aspirin along with clopidogrel, prasugrel, or ticagrelor. This is well known that aspirin
Muhammad Naufal Hibatullah   +2 more
doaj   +1 more source

Ticagrelor Versus Prasugrel in Acute Coronary Syndrome: Real-World Treatment and Safety

open access: yesMedicines
Introduction: A direct head-to-head comparison between potent P2Y12 inhibitors: prasugrel versus ticagrelor is still lacking. Purpose: In this single-center study, we sought to address the efficacy and safety of these two third-generation antiplatelet ...
Fadel Bahouth   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy