Results 1 to 10 of about 149,648 (111)
Stability-Indicating LC Method for the Determination of Prasugrel Hydrochloride in Pharmaceutical Dosage Form. [PDF]
Sci Pharm, 2012 A simple, rapid and precise method was developed for the quantitative estimation of prasugrel hydrochloride in pharmaceutical dosage form. A chromatographic separation of prasugrel and its degradants was achieved with Zorbax XDB C(8), 150 × 4.6 mm, 3.5μm analytical column using aqueous solution of 0.05 M ammonium acetate pH 4.5 with acetic acid ...
Ahirrao VK +7 more
europepmc +5 more sources
Process validation of prasugrel hydrochloride tablet USP
International Journal of Pharmaceutical Chemistry and Analysis, 2020 Process validation is an essential part for the safety and quality of the drug products. Validation act as guidance that is intended to assist manufacturers in understanding quality management system requirements concerning process validation. It is a fundamental component for assuring the quality system used by pharmaceutical industries.
Yamuna Choudhary, Anju Goyal, Anju Goyal
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Pharmaceutics and Pharmacology Research, 2022 The objective of this study was to investigate nanosuspensions for enhancing the solubility and dissolution rate of Prasugrel HCl (PHCl) so as to reduce the fluctuations in its oral bioavailability. Prasugrel Hydrochloride nanosuspensions were prepared using evaporative precipitation method. After preparation, various nanosuspensions were characterized
R. Devara
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Preparation and Evaluation of Multi-Particulate System (Pellets) of Prasugrel Hydrochloride [PDF]
Open Pharmaceutical Sciences Journal, 2015 Multiparticulate systems (pellets) of prasugrel hydrochloride were prepared by extrusion spheronization method using MCC (micro crystalline cellulose). Optimum spheronization time and method of drying were selected as the process parameters for the preparation of final batches.
Navjot Kanwar, Rakesh Kumar, V.R. Sinha
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Identification and Synthesis of Impurities Formed During Prasugrel Hydrochloride Preparation
Asian Journal of Chemistry, 2013 Prasugrel hydrochloride is designated chemically as 5[1(RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxyethyl]-4,5,6,7tetrahydrothieno[3,2-c]pyridine-2-yl acetate hydrochloride (1).
T. Umasankara Sastry +3 more
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An Improvement to the Preparation of Prasugrel Hydrochloride
Journal of Chemical Research, 2013 An efficient synthesis of prasugrel, a thienopyridine ADP-receptor antagonists, is described. A thienopyridine inter-mediate was prepared by N-protection, boric acid substitution and N-substitution. After acid hydrolysis of the methyl ether and subsequent acetylation, prasugrel was obtained with a total yield of 50% after seven linear steps from 4,5,6,
Wenhua Ou +4 more
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Journal of Liquid Chromatography & Related Technologies, 2018 New high-performance liquid chromatography method was developed for the determination of prasugrel HCl-related substances. Impurity profile of prasugrel HCl was established by studying the degradation profile of it as an active pharmaceutical ingredient, for the first time, in the tablet form.
Arar, Sharif +2 more
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Estimation Of Prasugrel Hydrochloride In Bulk Dosage Form
Journal of Medical Pharmaceutical And Allied Sciences, 2020 J. Tejaswi
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International Journal of Scientific Research and Reviews, 2019 Warkad S. S +4 more
semanticscholar +3 more sources