Results 11 to 20 of about 755 (138)

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +165 more
wiley   +1 more source

Recent progress in orodispersible films‐mediated therapeutic applications: A review

open access: yesMedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian   +5 more
wiley   +1 more source

Successful use of portable extracorporeal carbon-dioxide removal in a patient with uncontrollable hypercapnoea [PDF]

open access: yes, 2007
OBJECTIVE: To assess the long term implications of four alternative approaches to postpartum perineal repair. DESIGN: A stratified randomised controlled trial using a 2x2 factorial design.
Peek, G   +3 more
core   +4 more sources

A Space‐Dependent ‘Enzyme‐Substrate’ Type Probe based on ‘Carboxylesterase‐Amide Group’ for Ultrafast Fluorescent Imaging Orthotopic Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 10, Issue 8, March 15, 2023., 2023
Based on the “substrate‐hydrolysis enzymatic reaction” approach, a fluorescent probe toward carboxylesterase with ultra‐rapid response rate is designed and developed, which is allowed to specifically image orthotopic liver tumor rather than metastatic tumor and distinguish human primary liver cancer tissue from adjacent ones.
Ying Wen   +5 more
wiley   +1 more source

Process validation of prasugrel hydrochloride tablet USP

open access: yesInternational Journal of Pharmaceutical Chemistry and Analysis, 2020
Process validation is an essential part for the safety and quality of the drug products. Validation act as guidance that is intended to assist manufacturers in understanding quality management system requirements concerning process validation. It is a fundamental component for assuring the quality system used by pharmaceutical industries.
Yamuna Choudhary, Anju Goyal, Anju Goyal
openaire   +2 more sources

Acute myocardial infarction complicated by purulent pericarditis: A case report

open access: yesClinical Case Reports, Volume 11, Issue 1, January 2023., 2023
Although bleeding complications are the primary cause of sudden cardiac tamponade in acute myocardial infarction, purulent pericarditis is also a possibility. It is rare but must be diagnosed promptly because it can worsen rapidly by sepsis. Abstract A man with persistent dyspnea was brought to our hospital in an emergency.
Yamato Tamura, Takehisa Abe
wiley   +1 more source

Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2022, Issue 1, 2022., 2022
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease outbreak, there has been an increasing interest in discovering potential therapeutic agents for this disease. In this regard, we conducted a systematic review through an overview of drug development (in silico, in vitro, and in vivo) for treating COVID‐19. Methods.
Sarah Mousavi   +4 more
wiley   +1 more source

JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias

open access: yes, 2022
Journal of Arrhythmia, Volume 38, Issue 6, Page 833-973, December 2022.
Katsushige Ono   +56 more
wiley   +1 more source

Iron‐Catalyzed Carbonylation Reactions with Carbon Monoxide

open access: yesAngewandte Chemie, Volume 137, Issue 36, September 1, 2025.
Recent developments in iron‐catalyzed carbonylative transformations using CO as a C₁ feedstock are summarized in this minireview. Reaction mechanisms of selected reactions and the potential for further advancements in this field are also discussed. Abstract The utilization of carbon monoxide (CO) as an inexpensive and indispensable C1 feedstock for the
Kangkang Sun   +3 more
wiley   +2 more sources

Concomitant Polymorphism of Prasugrel Hydrochloride in Reactive Crystallization

open access: yes, 2016
Concomitant polymorphism of prasugrel hydrochloride was investigated in reactive batch crystallization experiments at 20 and 40 °C. The solubility of prasugrel hydrochloride form I and form II was experimentally determined.
Jingkang Wang (1758835)   +8 more
core   +1 more source

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