Results 11 to 20 of about 1,084 (158)

Capnocytophaga canimorsus Septicemia With Sepsis-Induced Coagulopathy and Endocarditis [PDF]

open access: yesCase Reports in Infectious Diseases, Volume 2024, Issue 1, 2024.
Capnocytophaga canimorsus is a rare cause of serious infections with a high mortality of 10% to 30%. It is usually found in the oral cavity of cats and dogs and can cause severe sepsis in immunocompromised patients.
Bals, Robert   +9 more
core   +2 more sources

Fatal myocardial infarction investigated using contrast‐enhanced postmortem computed tomography: A case report

open access: yesClinical Case Reports, Volume 11, Issue 12, December 2023., 2023
Autopsy imaging (AI). (A) Plain CT shows massive pleural effusion (arrows) of 50 HU on AI, which implied that the fluid was blood. (B) After a few sets of chest compression, CT showed the contrast agent flow (arrow) from the cardiac cavity into the pericardium. AI, autopsy imaging; CT, computed tomography; HU, Hounsfield unit.
Kohei Aoe   +4 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +165 more
wiley   +1 more source

Recent progress in orodispersible films‐mediated therapeutic applications: A review

open access: yesMedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian   +5 more
wiley   +1 more source

A Space‐Dependent ‘Enzyme‐Substrate’ Type Probe based on ‘Carboxylesterase‐Amide Group’ for Ultrafast Fluorescent Imaging Orthotopic Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 10, Issue 8, March 15, 2023., 2023
Based on the “substrate‐hydrolysis enzymatic reaction” approach, a fluorescent probe toward carboxylesterase with ultra‐rapid response rate is designed and developed, which is allowed to specifically image orthotopic liver tumor rather than metastatic tumor and distinguish human primary liver cancer tissue from adjacent ones.
Ying Wen   +5 more
wiley   +1 more source

Acute myocardial infarction complicated by purulent pericarditis: A case report

open access: yesClinical Case Reports, Volume 11, Issue 1, January 2023., 2023
Although bleeding complications are the primary cause of sudden cardiac tamponade in acute myocardial infarction, purulent pericarditis is also a possibility. It is rare but must be diagnosed promptly because it can worsen rapidly by sepsis. Abstract A man with persistent dyspnea was brought to our hospital in an emergency.
Yamato Tamura, Takehisa Abe
wiley   +1 more source

Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2022, Issue 1, 2022., 2022
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease outbreak, there has been an increasing interest in discovering potential therapeutic agents for this disease. In this regard, we conducted a systematic review through an overview of drug development (in silico, in vitro, and in vivo) for treating COVID‐19. Methods.
Sarah Mousavi   +4 more
wiley   +1 more source

Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial [PDF]

open access: yes, 2017
Pharmacogenomic testing has become increasingly widespread. However, there remains a need to bridge the gap between test results and providers lacking the expertise required to interpret these results.
Desta, Zeruesenay   +3 more
core   +1 more source

Effects of single versus dual antiplatelet therapy on the adverse events after transcatheter aortic valve implantation: A meta‐analysis

open access: yesClinical Cardiology, Volume 44, Issue 12, Page 1718-1728, December 2021., 2021
Abstract Dual antiplatelet therapy (DAPT) was currently recommended for transcatheter aortic valve implantation (TAVI) postoperative management in clinical application. However, POPular‐TAVI trial showed DAPT increased the incidence of adverse events compared to single antiplatelet therapy (SAPT). Herein, we performed a meta‐analysis to investigate the
Shengqin Yu   +3 more
wiley   +1 more source

P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential [PDF]

open access: yes, 2012
P2Y receptors for extracellular nucleotides are coupled to activation of a variety of G proteins and stimulate diverse intracellular signaling pathways that regulate functions of cell types that comprise the central nervous system (CNS).
Erb, Laurie   +3 more
core   +1 more source

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