Results 11 to 20 of about 755 (138)
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.Stephen P. H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Deron Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Davide Malfacini, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Khuraijam Dhanachandra Singh, Craig M. Smith, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Chengcan Yao, Richard D. Ye +165 morewiley +1 more sourceRecent progress in orodispersible films‐mediated therapeutic applications: A review
MedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023 The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract
Orodispersible ...Yu Tian, Jiangtao Lin, Hongshu Jing, Quan Wang, Zhihua Wu, Yourong Duan +5 morewiley +1 more sourceA Space‐Dependent ‘Enzyme‐Substrate’ Type Probe based on ‘Carboxylesterase‐Amide Group’ for Ultrafast Fluorescent Imaging Orthotopic Hepatocellular Carcinoma
Advanced Science, Volume 10, Issue 8, March 15, 2023., 2023 Based on the “substrate‐hydrolysis enzymatic reaction” approach, a fluorescent probe toward carboxylesterase with ultra‐rapid response rate is designed and developed, which is allowed to specifically image orthotopic liver tumor rather than metastatic tumor and distinguish human primary liver cancer tissue from adjacent ones.Ying Wen, Ning Jing, Min Zhang, Fangjun Huo, Zhuoyu Li, Caixia Yin +5 morewiley +1 more sourceProcess validation of prasugrel hydrochloride tablet USP
International Journal of Pharmaceutical Chemistry and Analysis, 2020 Process validation is an essential part for the safety and quality of the drug products. Validation act as guidance that is intended to assist manufacturers in understanding quality management system requirements concerning process validation. It is a fundamental component for assuring the quality system used by pharmaceutical industries.Yamuna Choudhary, Anju Goyal, Anju Goyalopenaire +2 more sourcesAcute myocardial infarction complicated by purulent pericarditis: A case report
Clinical Case Reports, Volume 11, Issue 1, January 2023., 2023 Although bleeding complications are the primary cause of sudden cardiac tamponade in acute myocardial infarction, purulent pericarditis is also a possibility. It is rare but must be diagnosed promptly because it can worsen rapidly by sepsis. Abstract
A man with persistent dyspnea was brought to our hospital in an emergency.Yamato Tamura, Takehisa Abewiley +1 more sourceNovel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2022, Issue 1, 2022., 2022 Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease outbreak, there has been an increasing interest in discovering potential therapeutic agents for this disease. In this regard, we conducted a systematic review through an overview of drug development (in silico, in vitro, and in vivo) for treating COVID‐19. Methods.Sarah Mousavi, Shima Zare, Mahmoud Mirzaei, Awat Feizi, Siddhartha Pati +4 morewiley +1 more sourceJCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias
, 2022 Journal of Arrhythmia, Volume 38, Issue 6, Page 833-973, December 2022.Katsushige Ono, Yu‐ki Iwasaki, Masaharu Akao, Takanori Ikeda, Kuniaki Ishii, Yasuya Inden, Kengo Kusano, Yoshinori Kobayashi, Yukihiro Koretsune, Tetsuo Sasano, Naokata Sumitomo, Naohiko Takahashi, Shinichi Niwano, Nobuhisa Hagiwara, Ichiro Hisatome, Tetsushi Furukawa, Haruo Honjo, Toru Maruyama, Yuji Murakawa, Masahiro Yasaka, Eiichi Watanabe, Takeshi Aiba, Mari Amino, Hideki Itoh, Hisashi Ogawa, Yasuo Okumura, Chizuko Aoki‐Kamiya, Jun Kishihara, Eitaro Kodani, Takashi Komatsu, Yusuke Sakamoto, Kazuhiro Satomi, Tsuyoshi Shiga, Tetsuji Shinohara, Atsushi Suzuki, Shinya Suzuki, Yukio Sekiguchi, Satoshi Nagase, Noriyuki Hayami, Masahide Harada, Tadashi Fujino, Takeru Makiyama, Mitsunori Maruyama, Junichiro Miake, Shota Muraji, Hiroshige Murata, Norishige Morita, Hisashi Yokoshiki, Koichiro Yoshioka, Kenji Yodogawa, Hiroshi Inoue, Ken Okumura, Takeshi Kimura, Hiroyuki Tsutsui, Wataru Shimizu, the Japanese Circulation Society and, Japanese Heart Rhythm Society Joint Working Group +56 morewiley +1 more sourceIron‐Catalyzed Carbonylation Reactions with Carbon Monoxide
Angewandte Chemie, Volume 137, Issue 36, September 1, 2025.Recent developments in iron‐catalyzed carbonylative transformations using CO as a C₁ feedstock are summarized in this minireview. Reaction mechanisms of selected reactions and the potential for further advancements in this field are also discussed. Abstract
The utilization of carbon monoxide (CO) as an inexpensive and indispensable C1 feedstock for the Kangkang Sun, Guo‐Ping Lu, Wei Han, Matthias Beller +3 morewiley +2 more sourcesConcomitant
Polymorphism of Prasugrel Hydrochloride in Reactive Crystallization
, 2016 Concomitant
polymorphism of prasugrel hydrochloride was investigated in reactive
batch crystallization experiments at 20 and 40 °C. The solubility
of prasugrel hydrochloride form I and form II was experimentally determined.Jingkang Wang (1758835), Chuang Xie (1755553), Wei Du (88790), Baohong Hou (1514521), Ying Bao (267477), Hongxun Hao (1479568), Qiuxiang Yin (1514518), Wei Chen (23863), Junbo Gong (400138) +8 morecore +1 more source