Results 21 to 30 of about 755 (138)

Effects of Solvent on Polymorph Formation and Nucleation of Prasugrel Hydrochloride

, 2016
Three intrinsic properties of solvent were used to evaluate the effects of solvent on polymorph formation of prasugrel hydrochloride. In situ Raman spectroscopy, FTIR, and powder X-ray diffraction were used to characterize two solvent-free polymorphs and
Chuang Xie (1755553), Wei Du (88790), Suping Ding (1600462), Ying Bao (267477), Xia Zhang (41398), Hongxun Hao (1479568), Qiuxiang Yin (1514518), Xiaowei Sun (318880), Meijing Zhang (1600459), Junbo Gong (400138)   +9 more
core   +1 more source

Meeting the UN Sustainable Development Goals with Mechanochemistry

Angewandte Chemie, Volume 136, Issue 50, December 9, 2024.
This minireview explores how mechanochemistry can address the United Nations Sustainable Development Goals. The potential of mechanochemistry to address climate change, energy scarcity, food insecurity and waste pollution by providing more efficient and environmentally friendly chemical processes is highlighted.
Jasna Alić, Moritz‐Caspar Schlegel, Franziska Emmerling, Tomislav Stolar   +3 more
wiley   +2 more sources

DEVELOPMENT AND EVALUATION OF PRASUGREL HYDROCHLORIDE FLOATING TABLETS

, 2019
The objective of the present work was to formulate and characterize floating drug delivery system of Prasugrel hydrochloride that releases the drug slowly up to 8 h in order to minimize its potential side effect bleeding and to improve the ...
Kotharapu, Rama Koteswararao, Lankalapalli, Srinivas   +1 more
core   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Prasugrel: Reassessing Its Role in Contemporary Antiplatelet Therapy

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Managing acute coronary syndrome (ACS) and atherosclerotic cardiovascular disease remains clinically challenging, requiring a careful balance between ischemic protection and bleeding risk. Antiplatelet therapy is central to the management, with aspirin serving as the cornerstone; however, selection of the second antiplatelet agent in dual antiplatelet ...
Yusof Kamisah, Hamat Hamdi Che Hassan, Nicholas B. Norgard   +2 more
wiley   +1 more source

Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications

Chemistry – A European Journal, Volume 31, Issue 67, December 1, 2025.
Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju, Davide Benedetto Tiz, Adrian Iles, Janez Košmrlj, Ross D. Jansen‐van Vuuren   +4 more
wiley   +1 more source

UEG Week 2023 Poster Presentations

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
wiley   +1 more source

Solution-Mediated Polymorphic Transformation of Prasugrel Hydrochloride from Form II to Form I

, 2016
In situ Raman spectroscopy was applied for the analysis of the solution-mediated polymorphic transformation of prasugrel hydrochloride from the metastable form II to the stable form I.
Chuang Xie (1755553), Wei Du (88790), Xiang Li (114679), Jiting Huang (1823260), Ying Bao (267477), Xia Zhang (41398), Hongxun Hao (1479568), Qiuxiang Yin (1514518), Junbo Gong (400138)   +8 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source

A randomized comparison of platelet reactivity in patients after treatment with various commercial clopidogrel preparations: The CLO-CLO trial

, 2012
Objectifs Le but de cette étude est de comparer l’effet sur l’agrégation plaquettaire de la molécule originale de clopidogrel (clopidogrel bisulfate [Plavix®]) aux molécules génériques (clopidogrel besylate [clopidogrel Sandoz®] et clopidogrel ...
Lehner, Cédric, Stauffer, Jean-Christophe, Togni, Mario, Lehmann, Sonja, Oberhänsli, Markus, Cook, Stéphane, Baeriswyl, Gérard, Puricel, Serban, Goy, Jean-Jacques   +8 more
core   +1 more source