Results 1 to 10 of about 30,204 (224)

Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial

Parasites & Vectors
Background Reliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance. Combination therapy targeting adult and juvenile schistosome worms is urgently needed to improve praziquantel ...
Charles O. Obonyo, Fredrick O. Rawago, Nicholas K. Makworo, Erick M. O. Muok   +3 more
doaj   +1 more source

Brønsted acid-mediated cyclization–dehydrosulfonylation/reduction sequences: An easy access to pyrazinoisoquinolines and pyridopyrazines

Beilstein Journal of Organic Chemistry, 2017
An efficient and alternative synthetic approach has been developed to prepare various N-(arylethyl)piperazine-2,6-diones from 4-benzenesulfonyliminodiacetic acid and primary amines using carbonyldiimidazole in the presence of a catalytic amount of DMAP ...
Ramana Sreenivasa Rao, Chinnasamy Ramaraj Ramanathan   +1 more
doaj   +1 more source

Human Schistosomiasis Resistance to Praziquantel in China: Should We Be Worried? [PDF]

, 2011
Edmund Y. W. Seto, Betty K. Wong, Ding Lu, Bo Zhong   +3 more
openalex   +1 more source

Baiting not-owned dogs against Echinococcus granulosus: innovative tools for integrated control

Parasitology
Cystic echinococcosis (CE), caused by the larval stage of the cestode Echinococcus granulosus, is one of the most widespread zoonoses in Mediterranean countries. Baiting not-owned dogs with praziquantel (PZQ), due to their key role in the maintaining the
Elena Ciccone, Antonio Bosco, Paola Pepe, Martina Nocerino, Nicola Lattero, Gerald Umhang, Laatamna AbdElkarim, Samia Lahmar, Yousra Said, Giorgio Saralli, Giuseppe Piegari, Maria Chiara Alterisio, Rania Baka, Smaragda Sotiraki, Franck Boué, Laura Rinaldi   +15 more
doaj   +1 more source

Case Report: Praziquantel-induced flare-up reaction in a rare case of diclofenac-induced probable DRESS comorbid with acute clonorchiasis: diagnostic and therapeutic challenges

Frontiers in Medicine
Drug reaction with eosinophilia and systemic symptoms (DRESS), a severe T-cell-mediated hypersensitivity with mortality up to 10%, may progress to life-threatening multi-organ failure and culminate in multiple drug hypersensitivity (MDH).
Wei Li, Kaizhou Huang, Kaizhou Huang, Ying Chen, Ying Chen, Yuping Huang, Yi Zheng, Yi Zheng, Minhua Zhong, Minhua Zhong, Kaiping Jiang, Kaiping Jiang, Xiaojun Ma, Xiaojun Ma   +13 more
doaj   +1 more source

Increases in Human T Helper 2 Cytokine Responses toSchistosoma mansoniWorm and Worm‐Tegument Antigens Are Induced by Treatment with Praziquantel [PDF]

, 2004
Sarah Joseph, Frances M. Jones, Klaudia Walter, Anthony J. C. Fulford, Gachuhi Kimani, Joseph K. Mwatha, Timothy Kamau, Henry C. Kariuki, Francis Kazibwe, Edridah M. Tukahebwa, Narcis B. Kabatereine, John H. Ouma, Birgitte J. Vennervald, David W. Dunne   +13 more
openalex   +1 more source

Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage

Frontiers in Immunology
BackgroundSchistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a key element of innate immunity, the complement system ...
Anna E. van Beek, Anna E. van Beek, Hannah Jeanguenat, Hannah Jeanguenat, Cécile Häberli, Cécile Häberli, Richard B. Pouw, Richard B. Pouw, Christina Lamers, Gábor Pál, Péter Gál, Christoph Q. Schmidt, Daniel Ricklin, Jennifer Keiser, Jennifer Keiser   +14 more
doaj   +1 more source

Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel

, 2021
Evgeny G. Chulkov, Emery Smith, Claudia M. Rohr, Nawal A. Yahya, Sang-Kyu Park, Louis Scampavia, Timothy Spicer, Jonathan S. Marchant   +7 more
openalex   +2 more sources

Cucurbita pepo Seed Oil Induces Microsatellite Instability and Tegumental Damage to Schistosoma mansoni Immature and Adult Worms In vitro

Infection and Drug Resistance, 2020
Amany Ibrahim Ammar, 1 Amira Fathy Afifi, 1 Abdallah Essa, 2, 3 Asmaa Galal-Khallaf, 4 Mostafa Mohamed Mokhtar, 5 Somaia Shehab-Eldeen, 2, 3 Amany Ahmed Rady 1 1Department of Medical Parasitology, Faculty of Medicine, Menoufia University, Shebin El Kom,
Ammar AI, Afifi AF, Essa A, Galal-Khallaf A, Mokhtar MM, Shehab-Eldeen S, Rady AA   +6 more
doaj  

Challenges and Proven Recommendations of Praziquantel Formulation [PDF]

, 2023
Deryl Nii Okantey Kuevi, Francis A. Acquah, Amy Amuquandoh, Andrew Papa Abbey   +3 more
openalex   +1 more source