Results 1 to 10 of about 23,061 (147)

Anthelmintic Resistance in Ancylostoma caninum: A Comprehensive Review. [PDF]

Vet Med Sci
This review summarizes the emergence of anthelmintic resistance in Ancylostoma caninum, with a focus on drug classes affected, global prevalence and resistance mechanisms. Early detection and integrated control strategies are essential to combat its spread.
Sönmez Hİ, Madak E, Karaer MC, Sarımehmetoğlu HO.   +3 more
europepmc   +2 more sources

Efficacy and safety of moxidectin, synriam, synriam-praziquantel versus praziquantel against schistosoma haematobium and S. mansoni infections: a randomized, exploratory phase 2 trial [PDF]

, 2016
Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or clinical ...
Barda, Beatrice, Coulibaly, Jean T., Hattendorf, Jan, Huwyler, Jörg, Keiser, Jennifer, Puchkov, Maxim   +5 more
core   +48 more sources

Analysis of miR‐10a and IFNG Expression Before and After Treatment for Chronic Schistosomiasis mansoni [PDF]

Parasite Immunol
ABSTRACT Mir‐10a acts in signalling pathways regulating transcription, translation, and RNA‐mediated gene silencing, while IFNG acts in the T‐cell receptor signalling pathway. Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis.
da Nóbrega D, Barreto A, dos Santos Souza R, do Ó K, de Lima R, Domingues A, Lopes E, de Morais C, Gomes E, Vasconcelos L.   +9 more
europepmc   +2 more sources

Spontaneous Pneumothorax Secondary to Pulmonary Paragonimiasis: A Case Report Highlighting Diagnostic Delay in Eastern Nepal. [PDF]

Respirol Case Rep
Here we present a 48‐year‐old farmer diagnosed with pleuropulmonary paragonimiasis complicated by spontaneous pneumothorax. This case highlights the diagnostic dilemmas posed and stresses the inclusion of parasitic diseases in the differential diagnosis, especially in resource‐poor settings and tuberculosis‐endemic countries, thus avoiding anti ...
Mahato AK, Shah S, Sah SK, Rupak KC, Adhikari B, Pokhrel A.   +5 more
europepmc   +2 more sources

Praziquantel in clonorchiasis and opisthorchiasis [PDF]

Tropenmedizin und Parasitologie, 1981
A single stool examination revealed pathogenic intestinal parasites in 462 (58%) of 796 vietnamese and cambodian refugees. 56 (7.0%) were infected with Clonorchis sinensis and/or Opisthorchis viverrini. These patients received Praziquantel in a dosage of
Lang, W., Löscher, Thomas, Nothdurft, H. D., Prüfer, L., Sonnenburg, F. von   +4 more
core   +3 more sources

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni [PDF]

, 2016
Natural selection acts on all organisms, including parasites, to maximise reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment.
Viana, Mafalda, Faust, Christina L., Haydon, Dan T., Webster, Joanne P., Lamberton, Poppy H.L.   +4 more
core   +13 more sources

Praziquantel (Droncit) is effective against diplostomosis of grasscarp Ctenopharyngodon idella and silver carp Hypophthalmichthys molitrix [PDF]

, 1991
In laboratory experiments praziquantel (Droncit) effectively destroyed metacercariae of Diplostomum spathaceum (s. l.) parasitizing the eye lens of grasscarp Ctenopharyngodon idella and silver carp Hypophthalmichthys molitrix.
Molnár, Kálmán, Székely, Csaba
core   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Jesse M. de Gooijer, Michael Woelfle, Jean-Paul Seerden, Kees Pouwer, Matthew H. Todd, Piero Olliaro   +5 more
openaire   +5 more sources

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]

, 2009
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE, Alonso, Baard, Barakat, Botros, Botros, Cioli, D. CIOLI, D. ENGELS, G. COLES, Keiser, L. A. TCHUEM TCHUENTÉ, L. PICA-MATTOCCIA, M. J. DOENHOFF, Mwanakasale, N'Goran, P. HAGAN, Pica-Mattoccia, S. BOTROS, Stohler, Utzinger, V. SOUTHGATE, Van Wyk   +22 more
core   +2 more sources

Praziquantel: A Review [PDF]

Journal of Veterinary Science & Technology, 2014
Praziquantel is a synthetic heterocyclic broad-spectrum anthelminthic agent effective against parasitic schistosome species as well as most other trematodes and adult cestodes. This article aims to present a comprehensive overview of studies concerning the drug history, structure, dosage, pharmacokinetics, side effects, toxicity, mechanism of action ...
Souad M. Alsaqabi, Wael M. Lotfy
openaire   +1 more source