Results 31 to 40 of about 29,034 (242)

Praziquantel coverage in schools and communities targeted for the elimination of urogenital schistosomiasis in Zanzibar: a cross-sectional survey [PDF]

, 2015
© 2015 Knopp et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any ...
Ali, SM, Ame, SM, Blair, L, Fenwick, A, Juma, S, Khamis, IS, Knopp, S, Mohammed, KA, Muhsin, J, Person, B, Rabone, M, Rollinson, D   +11 more
core   +2 more sources

Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis

Parasites & Vectors, 2011
Background Praziquantel has been used as first-line drug for chemotherapy of schistosomiasis since 1984. Besides praziquantel, artemether and artesunate have also been used for the control of this infectious disease since late 1990s.
Zhao Qin-Ping, Guo Yi, Dong Hui-Fen, Liu Rong, Jiang Ming-Sen   +4 more
doaj   +1 more source

Efficacy of Praziquantel for the Treatment of Human Schistosomiasis in Ethiopia: A Systematic Review and Meta-Analysis

Journal of Tropical Medicine, 2021
Background. Schistosomiasis is one of the neglected tropical diseases causing a serious human health problem in Ethiopia. Praziquantel is the only drug that has been used for the treatment of human schistosomiasis in the country.
Tamirat Hailegebriel, Endalkachew Nibret, Abaineh Munshea   +2 more
doaj   +1 more source

Does mass drug administration for the integrated treatment of neglected tropical diseases really work? Assessing evidence for the control of schistosomiasis and soil-transmitted helminths in Uganda [PDF]

, 2011
This paper was one of four papers commissioned to review the role of social sciences in NTD control by TDR, the Special Programme for Research and Training on Tropical Diseases, which is executed by WHO and co-sponsored by UNICEF, UNDP, the World Bank ...
A Dansio-Appiah, A Fenwick, A Fenwick, B Gryseels, B Gryseels, CJ Standley, D Engels, D Yu, DH Molyneux, DH Molyneux, EP Renne, FM Fleming, G Yamey, I Harper, J Hastings, J Utzinger, JH Kolaczinski, L Manderson, M Leach, M Parker, M Parker, M Parker, M Parker, M Yahya, MA Brady, Melissa Parker, MN Katabarawa, MN Katabarwa, N Rees, NB Kabatereine, NB Kabatereine, NB Kabatereine, PJ Hotez, PJ Hotez, PJ Lammie, RGN Lubanga, S Brooker, S Knopp, T Allen, T Allen, T Allen, T Allen, T Allen, T Allen, Tim Allen, TL-A Tchuente, U Amazigo, World Health Organization, Y Coulibaly   +48 more
core   +4 more sources

Misoprostol in the management of the third stage of labour in the home delivery setting in rural Gambia: a randomised controlled trial. [PDF]

, 2005
OBJECTIVE: To assess the effectiveness of 600 microg oral misoprostol on postpartum haemorrhage (PPH) and postpartum anaemia in a low income country home birth situation. DESIGN: Double blind randomised controlled trial.
Blum, Jennifer, Dampha, Yusupha, Morison, Linda, Sloan, Nancy, Sowe, Maimuna, Walraven, Gijs, Winikoff, Beverly   +6 more
core   +1 more source

Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats

Parasites & Vectors, 2018
Background Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is
Feli M. Walther, Petr Fisara, Rainer K. A. Roepke   +2 more
doaj   +1 more source

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas [PDF]

, 2015
Background: Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests.
Bossuyt, P.M.M., Gopalakrishna, G., Lamberton, P., Leeflang, M.M.G., Ochodo, E.A., Polman, K., Reitsma, J.B., Spek, B., van Lieshout, L.   +8 more
core   +3 more sources

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

Nature Communications, 2017
Schistosomiasis is caused by infection with the flatworm Schistosoma, and praziquantel is the drug of choice for its treatment. Here, Chan and colleagues identify praziquantel as a ligand for the human serotoninergic 5-HT2B G-protein-coupled receptor ...
John D. Chan, Pauline M. Cupit, Gihan S. Gunaratne, John D. McCorvy, Yang Yang, Kristen Stoltz, Thomas R. Webb, Peter I. Dosa, Bryan L. Roth, Ruben Abagyan, Charles Cunningham, Jonathan S. Marchant   +11 more
doaj   +1 more source

Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Infectious Diseases of Poverty, 2017
Background Mass drug administration of praziquantel is the World Health Organization’s endorsed control strategy for schistosomiasis. A decade of annual treatments across sub-Saharan Africa has resulted in significant reductions of infection prevalence ...
Poppy H.L. Lamberton, Christina L. Faust, Joanne P. Webster   +2 more
doaj   +1 more source

Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis

Frontiers in Immunology, 2021
Despite the enormous morbidity attributed to schistosomiasis, there is still no vaccine to combat the disease for the hundreds of millions of infected people.
Mark S. Pearson, Bemnet A. Tedla, Luke Becker, Rie Nakajima, Al Jasinskas, Takafira Mduluza, Takafira Mduluza, Francisca Mutapi, Francisca Mutapi, Claude Oeuvray, Beatrice Greco, Javier Sotillo, Javier Sotillo, Philip L. Felgner, Alex Loukas   +14 more
doaj   +1 more source