Results 61 to 70 of about 141,118 (333)

Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women [PDF]

, 2011
The early closure of a clinical trial assessing the effectiveness of oral antiretroviral pre-exposure prophylaxis (PrEP) in women, FEM-PrEP, is a substantial setback for HIV prevention.
Abdool Karim, Angela DM Kashuba, Dumond, Grant, Karim, Lise Werner, Quarraisha Abdool Karim, Salim S Abdool Karim   +7 more
core   +2 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Assessment of acceptance and associated factors of HIV pre-exposure prophylaxis among commercial female sex workers in drop-in centers selected sub-cities of Addis Ababa, Ethiopia

Frontiers in Public Health
BackgroundGlobally, female sex workers (FSWs) face high risk of HIV, particularly in regions like sub-Saharan Africa. In Ethiopia and Addis Ababa, the impact is significant.
Trhas Tadesse Berhe, Elefie Asfaw Asfaw, Getachew Weldyohanes Tedla   +2 more
doaj   +1 more source

Baseline Preferences for Daily, Event-Driven, or Periodic HIV Pre-Exposure Prophylaxis among Gay and Bisexual Men in the PRELUDE Demonstration Project

Frontiers in Public Health, 2017
IntroductionThe effectiveness of daily pre-exposure prophylaxis (PrEP) is well established. However, there has been increasing interest in non-daily dosing schedules among gay and bisexual men (GBM).
Stefanie J. Vaccher, Christopher Gianacas, David J. Templeton, David J. Templeton, Isobel M. Poynten, Bridget G. Haire, Catriona Ooi, Catriona Ooi, Rosalind Foster, Rosalind Foster, Anna McNulty, Anna McNulty, Andrew E. Grulich, Iryna B. Zablotska, On Behalf of the PRELUDE Study Team, Andrew Carr, Andrew Grulich, Anna McNulty, Brent Mackie, Cathy Pell, Catriona Ooi, Cheung (Yvonne) Ching, Chris Gianacas, David Templeton, Dean Murphy, Edwina Wright, Garrett Prestage, Isobel (Mary) Poynten, John de Wit, John Kaldor, John McAllister, Kenneth Mayer, Mark Bloch, Martin Holt, Nathan Ryder, Rebecca Guy, Rosalind Foster, Stefanie Vaccher   +37 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Impact of Educational Intervention Measures on Knowledge regarding HIV/ Occupational Exposure and Post Exposure Prophylaxis among Final Year Nursing Students of a Tertiary Care Hospital in Central India [PDF]

, 2010
Amongst the different Health Care Personnel nurses are at a greater risk of being accidentally exposed to HIV and other Blood Borne Pathogens. The present study was conducted among 50 final year nursing students of a Medical College Hospital to assess ...
Baghel, SS, Dixit, S, Jaiswal, S, Khatri, AK, Saroshe, S, Sengar, SS, Soni, S, Taneja, G   +7 more
core   +1 more source

Will I? won't I? Why do men who have sex with men present for post-exposure prophylaxis for sexual exposures? [PDF]

, 2008
Background: Failures of post-exposure prophylaxis following sexual exposure (PEPSE) to prevent seroconversion have been reported and are often associated with ongoing risk exposure.
Fisher, M, Llewellyn, Carrie, Nambiar, K, Nixon, E, Perry, N, Richardson, D, Sayer, C   +6 more
core   +2 more sources

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Transformation of Australian Community Pharmacies Into Good Clinical Practice Compliant Trial Pharmacies for HIV Pre-Exposure Prophylaxis

Frontiers in Pharmacology, 2019
Background: In Australia, clinical trial drugs are conventionally dispensed through clinical trial pharmacies only, while community pharmacies dispense drugs approved by Australia’s regulatory body.
Luxi Lal, Luxi Lal, Luxi Lal, Kathleen Ryan, Kathleen Ryan, Iris Yi Liu, Brian Price, Timmy Lockwood, Ivette Aguirre, Peter Slobodian, Ada Lam, Manoj Vassan, Kie Lim, John Silverii, Joseph Tesoriero, Johnny Phu, Wan Lim, Bharathy Naidoo, Nick Russell, Matthew Rundle, Rowan Sewell, Craig Cooper, Alexander Hardman, Martin Quinn, Anne Mak, Edwina J. Wright, Edwina J. Wright, Edwina J. Wright, Edwina J. Wright   +28 more
doaj   +1 more source

Exploring Pre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) Knowledge in Incarcerated Men

American Journal of Men's Health, 2022
People who are incarcerated have a disproportionately high risk of contracting human immunodeficiency virus (HIV). While there is no known cure for HIV, there are biomedical approaches that can successfully manage the virus and prevent its transmission ...
Pamela Valera, Zaire S. Ali, Diamond Cunningham, Christopher McLaughlin, Sebastian Acevedo   +4 more
doaj   +1 more source