Results 101 to 110 of about 215,557 (335)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Galaxies, 2019 Stellar evolution theory is most uncertain for massive stars. For reliable predictions of the evolution of massive stars and their final fate, solid constraints on the physical parameters, and their changes along the evolution and in different ...
Michaela Kraus
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Magnetic Activity of Pre-main Sequence Stars [PDF]
Symposium - International Astronomical Union, 2004 I review here recent advances in our understanding of magnetic activity in pre-main sequence (PMS) protostars and T Tauri stars. Results are based on recent imaging, spectroscopic and temporal studies of nearby star forming regions from the Chandra X — ray Observatory and XMM — Newton, including a first look at an ultradeep Chandra exposure of the ...
openaire +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Discovery of magnetic fields in the very young, massive stars W601 (NGC 6611) and OI 201 (NGC 2244)
, 2008 Context: Recent spectropolarimetric observations of Herbig Ae/Be stars have yielded new arguments in favour of a fossil origin for the magnetic fields of intermediate mass stars.
Balog +34 more
core +3 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Characterizing the X-ray Emission of Intermediate-Mass Pre-Main-Sequence Stars
, 2021 Evan Haze Nuñez +4 more
openalex +1 more source
Lithium and chromospherically active single giants [PDF]
Nine chromospherically active single K giants were identified from surveys of chromospherically active stars. The stars have v sin i's ranging from 6 to 46 km/sec.
Fekel, Francis C.
core +1 more source