Results 271 to 280 of about 14,806,844 (291)

Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: a systematic review and meta-analysis

Journal of Antimicrobial Chemotherapy, 2022
Abstract Background Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines for HIV treatment, there is a need for an updated systematic ...
Alex J Ntamatungiro, Juliana Kagura, Maja Weisser, Joel M Francis   +3 more
openaire   +3 more sources

Genotyping and Pre-treatment drug resistance surveillance among ART- naive HIV-1 patients in Tunisia.

Drug resistance to Human Immunodeficiency Virus (HIV) is a major factor in treatment failure. Although this resistance is mostly related to drug exposure, treatment-naïve patients living with HIV have also been shown to develop primary drug resistance.
Ibtihel Smeti, Salma Mhalla, Ikbel Kooli, Yosr Kadri, Hajer Rhim, Ons Haddad, Amel Nabli, Nabil Abid, Mohamed Chakroun, Maha MASTOURI   +9 more
openaire   +1 more source

Recent HIV-1 infection and pre-treatment HIV drug resistance among adults initiating antiretroviral therapy in rural Tanzania

International Journal of STD & AIDS
Background New HIV-1 infections continue to pose a major challenge to ending the HIV epidemic and may facilitate the transmission of drug-resistant strains. In this study, we aimed to determine the proportion of recent HIV-1 infections (RHI) among individuals initiating HIV care at a rural referral hospital in ...
Alex J. Ntamatungiro, Joel M. Francis, Dorcas Mnzava, Robert Ndege, Prosper S. Njau, James Okuma, Fiona Vanobberghen, Daniel H. Paris, Juliana kagura, Maja Weisser   +9 more
openaire   +2 more sources

Abstract 1196: A pre-treatment cfDNA methylation signature linking prognosis and drug-resistance biology in pancreatic ductal adenocarcinoma.

Cancer Research
Abstract Pre-treatment risk-stratification of pancreatic ductal adenocarcinoma (PDAC) can individualize response monitoring and streamline trial triage. We refined the previously reported treatment resistance-associated, literature-curated protein-informed cell-free DNA (cfDNA) methylation signature for baseline prognostication ...
Ashish Manne, Lianbo Yu, Wancai Yang, M Khalid Khan Niazi, Ravi Paluri, Anup Kasi, Prachi Bajpai, Alejandro Leyva, Upender Manne   +8 more
openaire   +1 more source

High Levels of Pre-Treatment HIV Drug Resistance in Zimbabwe: Is this a Threat to HIV/AIDS Control?

Journal of AIDS and HIV Treatment, 2021
openaire   +1 more source

Cost-effectiveness of oral pre-exposure prophylaxis and expanded antiretroviral therapy for preventing HIV infections in the presence of drug resistance among men who have sex with men in China: A mathematical modelling study

The Lancet Regional Health - Western Pacific, 2022
Zhihang Peng, Mingwang Shen, Yi Yin
exaly  

Pre-treatment HIV-drug resistance associated with virologic outcome of first-line NNRTI-antiretroviral therapy: A cohort study in Kenya

EClinicalMedicine, 2020
Michael Chung, Robert W Coombs, James N Kiarie   +2 more
exaly  

Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence

Cancer Letters, 2023
exaly  

Antiretroviral therapy and pre-exposure prophylaxis: combined impact on HIV transmission and drug resistance in South Africa.

Journal of Infectious Diseases, 2013
Ume L Abbas, John W Mellors, Robert Glaubius   +2 more
exaly  

Cost-effectiveness analysis of pre-ART HIV drug resistance testing in Kenyan women

EClinicalMedicine, 2020
Ingrid Beck, Lisa M Frenkel, Michael Chung   +2 more
exaly