Results 41 to 50 of about 3,707 (182)

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Establishment and implementation of an improvement plan using Lean Six Sigma methodology to minimize variation in ordering laboratory tests

open access: yesJournal of the Arab Society for Medical Research, 2022
Background/aim Ordering laboratory (laboratory) tests by physicians is a part of the pre-preanalytical laboratory phase, which is a high error-prone process.
Salwa H Gomaa   +4 more
doaj   +1 more source

Preanalytical factors affecting the plasma and serum levels of circulating microRNAs

open access: yesКардиоваскулярная терапия и профилактика
Circulating microribonucleic acids (microRNAs) are promising biomarkers of various diseases, but their clinical laboratory use requires highly sensitive, reproducible, reliable and sustainable methods for their accurate plasma and serum quantification ...
E. A. Sotnikova   +2 more
doaj   +1 more source

GC × GC‐TOF MS and Sensory Profiling of Aroma Compounds in Magnolia Species: Effects of Processing Methods on Volatile Retention in M. wufengensis

open access: yesFlavour and Fragrance Journal, EarlyView.
The first comparative analysis of Magnolia scents reveals that M. wufengensis is characterised by a high aldehyde content, exhibiting a fresh, sweet, and fruity fragrance profile. Furthermore, freeze‐drying preserves 6.7 times more 2‐nonenal compared to shade‐drying, highlighting its superior efficacy in retaining key volatile compounds.
Xiaole Wang   +7 more
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon   +5 more
wiley   +1 more source

Quality indicators of the pre-analytical phase [PDF]

open access: yesJournal of Medical Biochemistry, 2012
Quality indicators are tools that allow the quantification of quality in each of the segments of health care in comparison with selected criteria. They can be defined as an objective measure used to assess the critical health care segments such as, for ...
Majkić-Singh Nada, Šumarac Zorica
doaj  

Continual Improvement in Clinical Bacteriology Laboratory with Quality Indicators: A Retrospective Observational Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Healthcare management is undergoing significant changes with the evolution of new and re-emerging infections. A clinical microbiologist plays an important role in giving an accurate and timely report to the clinicians.
Mrudul Randive   +7 more
doaj   +1 more source

Prolonged Turnaround Time of the Hematology Laboratory and Related Factors in the South Gondar Zone, North West Ethiopia, Multi‐Centered Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Long turnaround times were prevalent in the hematology laboratories of South Gonder zone hospitals, predominantly as a result of staff incompetence. Clotted blood samples, low blood fill levels, and the day of the week were significant factors linked to delays, with samples collected on Friday having a higher likelihood of prolonged turnaround time ...
Birhanemaskal Malkamu   +19 more
wiley   +1 more source

Performance of a Deep Learning Algorithm for Melanoma Classification Across Diverse Dermoscopic and Tele‐Dermatology Datasets

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Early detection of melanoma significantly boosts patient survival rates. Deep learning has demonstrated dermatologist‐level accuracy in assessing pigmented skin lesions by analysing images at the pixel level. However, these neural networks may face challenges with ‘real‐life’ images due to limited training data and image artefacts ...
Marianne Zanchetta   +15 more
wiley   +1 more source

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p.A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis   +213 more
wiley   +1 more source

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