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Tolerance of Probiotics and Prebiotics

Journal of Clinical Gastroenterology, 2004
The clinical efficacy of probiotics and prebiotics has been proved in several clinical settings. The authors review their proved or potential side effects. Probiotics as living microorganisms may theoretically be responsible for 4 types of side effects in susceptible individuals: infections, deleterious metabolic activities, excessive immune ...
Philippe Seksik, Philippe Marteau
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Fate of Prebiotic Adenine

Astrobiology, 2001
Equilibrium adsorption isotherm data for the purine base adenine has been obtained on several prebiotically relevant minerals by frontal analysis using water as a mobile phase. Adenine is far displaced toward adsorption on pyrite (FeS2), quartz (SiO2), and pyrrhotite (FeS), but somewhat less for magnetite (Fe3O4) and forsterite (Mg2SiO4). The prebiotic
Corey A. Cohn   +4 more
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Prebiotic Synthesis on Minerals: Bridging the Prebiotic and RNA Worlds

The Biological Bulletin, 1999
An array of experimental findings suggest that the simple molecules required for the origin of life may have been available on the primitive Earth. The well-known MillerUrey electric discharge experiment yields HCN, amino acids, and carboxylic acids (1). Carbonaceous meteorites contain over 70 amino acids, some heterocyclic compounds, including purines,
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Introduction to Prebiotics

2014
Most of our understanding of the human colonic microbiota is derived from studying the microbial contents of fecal samples, because it is impractical to access the human large intestine during normal digestion, and as an alternative, bacteria detected in feces are most representative of populations present in distal region of the intestine. The colonic
Helena M. R. T. Parracho   +3 more
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An overview of probiotics and prebiotics

Nursing Standard, 2007
This article reviews the origins and background of probiotics. Evidence for the potential mechanisms of probiotics and prebiotics, and their interactions with the gastrointestinal tract and the immune system are discussed. Evidence is examined for the use of probiotics to treat infantile diarrhoea, irritable bowel syndrome, inflammatory bowel disease ...
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Probiotics, Prebiotics, and Synbiotics

2008
According to the German definition, probiotics are defined viable microorganisms, sufficient amounts of which reach the intestine in an active state and thus exert positive health effects. Numerous probiotic microorganisms (e.g. Lactobacillus rhamnosus GG, L. reuteri, bifidobacteria and certain strains of L. casei or the L.
Michael de Vrese, Jürgen Schrezenmeir
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Prebiotics in obesity.

Panminerva medica, 2015
Obesity was probably rare in ancient times, with the current increase starting in the Industrial Revolution of the eighteenth century, and becoming much more widespread from about 1950, so concurrent with the increased consumption of carbohydrates from cereals in the Green Revolution.
Carnahan, Sharyn   +3 more
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Prebiotic Synthesis of Methionine

Science, 1972
Methionine has been shown to be a product of the action of a spark discharge on a simulated primitive earth atmosphere containing CH 4 , N 2 , NH 3 , H 2 O, and H 2 S or CH 3 SH.
Stanley L. Miller, James E. Van Trump
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The prebiotic chemistry of nucleotides

Origins of Life, 1984
Diiminosuccinonitrile (DISN), formed by the oxidation of diaminomaleonitrile (DAMN), has been investigated as a potential prebiotic phosphorylating agent. DISN effects the cyclization of 3'-adenosine monophosphate to adenosine 2', 3'-cyclic phosphate in up to 39% yield. The mechanism of this reaction was investigated.
William J. Hagan   +2 more
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The evolution of the prebiotic atmosphere

Origins of Life, 1984
One-dimensional radiative convective and photochemical models are used to estimate the vertical temperature structure and composition of the earth's prebiotic atmosphere. Greatly enhanced CO2 levels (100-1000 times present) are required to keep the mean surface temperature above freezing in the face of decreased solar luminosity during the earth's ...
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