Translation‐Promoting Effects of RNA Template Overhangs in the Absence of Ribosomes
Ribosome‐free translation of an RNA sequence into a peptide sequence can be controlled by the folding of the template strand. Overhang sequences forming a triplex structure with the templating region and the peptidoyl RNA in pH‐dependent manner increase yields up to 40‐fold through entropic effects and mixed anhydride formation, allowing for controlled,
Nikolaos Giannakopoulos +2 more
wiley +2 more sources
Can the origin of biosynthetic routes be explained by a Frankenstein's monster-like spontaneous assembly of prebiotic reactants? [PDF]
Negrón-Mendoza A +2 more
europepmc +1 more source
Abstract The gastrointestinal (GI) microbiota and GI barrier integrity are hypothesised to contribute to exertional heat illness (EHI) aetiology. We compared the faecal microbiome, GI barrier integrity, inflammation and thermoregulation of 29 recent (∼4 months) EHI patients (a group with elevated EHI risk) and 29 control individuals without prior EHI ...
Alex A. M. Gould +13 more
wiley +1 more source
Selection for Molecularly Complementary Modules (MCMs) Drives the Origins and Evolution of Pleiofunctional, Epistatic Interactomes (PEIs). [PDF]
Root-Bernstein R.
europepmc +1 more source
The protective effect of probiotic/prebiotic consumption against fatigue in the general population is modulated by BMI: an analysis of mediating and moderating effects based on NHANES. [PDF]
Wang Y +10 more
europepmc +1 more source
The Pyruvate-Glyoxalate Pathway as a Toxicity Assessment Tool of Xenobiotics: Lessons from Prebiotic Chemistry. [PDF]
Gagné F, André C.
europepmc +1 more source
Current state of nutritional psychiatry: A scoping review of randomized controlled trials. [PDF]
Nagamine T.
europepmc +1 more source
Moisture sorption isotherms and thermodynamic properties of isomaltulose‐enriched mango
Abstract Background Moisture sorption isotherms and thermodynamic parameters are essential for designing and optimizing food processing and storage systems. This study aimed to evaluate these characteristics in untreated and osmotically treated mango slices, using isomaltulose and sucrose as osmotic agents.
Juliana Rodrigues do Carmo +5 more
wiley +1 more source
Open-Label, Prospective Study of a Prebiotic Gel Cream on Its Efficacy of Mild to Moderate Acne Management and Effects on the Functional Skin Microbiome. [PDF]
Afzal L +6 more
europepmc +1 more source

