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Determining the "Biosignature Threshold" for Life Detection on Biotic, Abiotic, or Prebiotic Worlds.

Astrobiology, 2021
The field of prebiotic chemistry has demonstrated that complex organic chemical systems that exhibit various life-like properties can be produced abiotically in the laboratory.
L. Barge   +3 more
semanticscholar   +1 more source

Prebiotics in foods

Current Opinion in Biotechnology, 2012
A wealth of information has been gathered over the past 15 years on prebiotics through experimental, animal and human studies, with the aim to understand the mechanism of actions and elucidate their beneficial health effects to the human host. Significant amount of evidence exists for their ability to increase the bioavailability of minerals and ...
Dimitris Charalampopoulos   +1 more
openaire   +3 more sources

Prebiotic Carbohydrates for Therapeutics

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2021
The food industry is constantly shifting focus based on prebiotics as health-promoting substrates rather than just food supplements. A prebiotic is “a selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastrointestinal microflora that confers benefits upon host well-being and health ...
Prapulla Siddalingaiya Gurudutt   +1 more
openaire   +2 more sources

prebiotic transamination

Origins of life and evolution of the biosphere, 1997
Biological amino acids and alpha keto acids directly condense with decarboxylation and transamination to yield product amino acids. This process is closely related to unusual amino acid decarboxylase enzymes in certain microorganisms and may represent a primordial mode of amino acid metabolism.
J C, Bishop, S D, Cross, T G, Waddell
openaire   +2 more sources

Synthetic connectivity, emergence, and self-regeneration in the network of prebiotic chemistry

Science, 2020
Mapping primordial reaction networks Chemists seeking to understand the origins of life have published a wide range of reactions that may have yielded the building blocks of proteins, nucleic acids, and lipids from simple precursors. Wołos et al. scoured
A. Wołoś   +8 more
semanticscholar   +1 more source

Effects of probiotic and prebiotic supplementation on metabolic parameters, liver aminotransferases, and systemic inflammation in nonalcoholic fatty liver disease: A randomized clinical trial.

Journal of Food Science, 2020
This study aimed to evaluate the clinical efficacy of probiotic and prebiotic supplementation on the metabolic parameters, liver enzymes, and inflammation in patients with nonalcoholic fatty liver disease (NAFLD).
Vahideh Behrouz   +3 more
semanticscholar   +1 more source

Prebiotics and Bone

2017
Recent advancements in food science have resulted in the extraction and synthesis of novel dietary fibers or prebiotics. Subsequently, great interest has emerged in developing strategies to improve metabolic conditions like osteoporosis by modulating the intestinal microbiome with fiber.
Connie M. Weaver, Corrie M. Whisner
openaire   +2 more sources

The Prebiotic Synthesis of Oligonucleotides

Origins of Life, 1974
This paper is primarily a review of recent developments in the abiotic synthesis of nucleotides, short chain oligonucleotides, and their mode of replication in solution. It also presents preliminary results from this laboratory on the prebiotic synthesis of thymidine oligodeoxynucleotides.
E. Stephen-Sherwood, J. Oró
openaire   +3 more sources

Is Cyanoacetylene Prebiotic?

Origins of life and evolution of the biosphere, 2002
Cyanoacetylene is an earlier intermediate in a proposed prebiotic synthesis of cytosine, while cyanoacetaldehyde is a later intermediate. There is no scientific basis for the claim that cyanoacetaldehyde is more plausibly prebiotic than cyanoacetylene in this context.
openaire   +3 more sources

Prebiotic Synthesis of Nucleotides

Origins of life and evolution of the biosphere, 2001
If an RNA-only world preceded more complex forms of life, then it is essential that the process whereby the first nucleotides were made be considered. Presumably there were no enzymes and no templates to facilitate the synthesis of the first nucleotides so another form of chemical evolution must have been involved. Answers to problems of this sort were
Timothy Mui, Geoffrey Zubay
openaire   +3 more sources

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