Results 71 to 80 of about 98,126 (343)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Scum of the Earth: A Hypothesis for Prebiotic Multi-Compartmentalised Environments
Life, 2021 Compartmentalisation by bioenergetic membranes is a universal feature of life. The eventual compartmentalisation of prebiotic systems is therefore often argued to comprise a key step during the origin of life.
Craig Robert Walton, Oliver Shorttle
doaj +1 more source
A prebiotic precursor to Life’s phosphate transfer system with an ATP analogue and histidyl peptide organocatalysts [PDF]
, 2023 Biochemistry is dependent upon enzyme catalysts accelerating key reactions. At the origin of life, prebiotic chemistry must have incorporated catalytic reactions.
Iris B. A., Smokers +4 more
core +2 more sources
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Borneo Journal of PharmacyPrebiotics, including carbohydrates and phenols, promote beneficial gut bacteria (probiotics). Red ginger (Zingiber officinale var. rubrum) rhizomes, rich in these compounds, have been traditionally used in medicine but their prebiotic potential remains
Fadil Rido Gumelar +2 more
doaj +1 more source
Prebiotic inulin-type fructans induce specific changes in the human gut microbiota
Gut, 2017 Objective Contrary to the long-standing prerequisite of inducing selective (ie, bifidogenic) effects, recent findings suggest that prebiotic interventions lead to ecosystem-wide microbiota shifts.
D. Vandeputte +7 more
semanticscholar +1 more source
Can synthetic biology shed light on the origin of life? [PDF]
, 2009 It is a most commonly accepted hypothesis that life originated from inanimate matter, somehow being a synthetic product of organic aggregates, and as such, a result of some sort of prebiotic synthetic biology.
Malaterre, Christophe
core
Advanced Science, EarlyView.An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong +4 more
wiley +1 more source
Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth
Cell Reports, 2020 SUMMARY Growing evidence supports the importance of gut microbiota in the control of tumor growth and response to therapy. Here, we select prebiotics that can enrich bacterial taxa that promote anti-tumor immunity.
Yan Li +14 more
semanticscholar +1 more source
Prebiotic Potential of Cereal Components
Foods, 2021 One type of functional food that has been receiving much attention is food rich in prebiotics. The old but still valid definition of prebiotics defines them as non-digestible food components that selectively stimulate the growth and/or activity of the ...
Reihaneh Abdi, I. Joye
semanticscholar +1 more source