Results 91 to 100 of about 2,831,810 (265)
, 2020 Can experimental prebiotic chemistry be improved by predictive and comprehensive computational approaches able to generalize the different suggested reductionist models? This fundamental question is addressed in the review “Prebiotic chemistry and origin
Saladino R
core +1 more source
Chemistry – A European Journal, EarlyView.Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil +7 more
wiley +1 more source
Prebiotic thiol-catalyzed thioamide bond formation
Geochemical TransactionsThioamide bonds are important intermediates in prebiotic chemistry. In cyanosulfidic prebiotic chemistry, they serve as crucial intermediates in the pathways that lead to the formation of many important biomolecules (e.g., amino acids).
Andrew S. Hyde, Christopher H. House
doaj +1 more source
Atmospheric Prebiotic Chemistry and Organic Hazes [PDF]
Current Organic Chemistry, 2013 Earth's atmospheric composition at the time of the origin of life is not known, but it has often been suggested that chemical transformation of reactive species in the atmosphere was a significant source of prebiotic organic molecules. Experimental and theoretical studies over the past half century have shown that atmospheric synthesis can yield ...
openaire +2 more sources
Chemistry – A European Journal, EarlyView.Cystine is unique among amino acids, in that the disulfide bond can allow intramolecular peptide bond formation. This cyclization offers potential advantages for intramolecular coupling selectivity in prebiotic peptide formation. ABSTRACT Treatment of cystine (the disulfide‐linked dimer of cysteine) with carbonyl sulfide (COS) results in the formation ...
Avinash Vicholous Dass +5 more
wiley +1 more source
Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions
Chemistry – A European Journal, EarlyView.Pyrophosphate acts as phosphorylating agent of guanosine under simple wet‐dry cycles without condensing agent and inorganic catalysts to afford cyclic guanosine monophosphate derivatives useful for oligomerization in prebiotic processes. ABSTRACT The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the ...
Martina Proietti +5 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Two previously uncharacterized heterocyclic imines, 3‐iminooxetane and 3‐oxazoline, are generated simultaneously by irradiation of 3‐azidooxetane under matrix isolation conditions. The infrared spectra provide reference data for future gas‐phase studies and may facilitate their search in the interstellar medium.
Mika Maehara +4 more
wiley +1 more source
The role of formamide in prebiotic chemistry
One of the most humbling aspects in prebiotic chemistry is the fact that we know remarkably little about the geochemical and geophysical conditions of the Earth at the origin of life. The pivotal Miller-Urey experiment suggested a possible path to set a first model of molecular evolution, that is energy (electric discharge) and matter (primitive ...
Saladino, Raffaele +2 more
openaire +5 more sources
Cosmic dust fertilization of glacial prebiotic chemistry on early Earth [PDF]
Earth’s surface is deficient in available forms of many elements considered limiting for prebiotic chemistry. In contrast, many extraterrestrial rocky objects are rich in these same elements.
Walton, Craig R. +9 more
core +7 more sources
Harnessing prebiotic formamide chemistry: a novel platform for antiviral exploration
Scientific ReportsViruses and host cells are intricately connected through a shared “chemical language” that may trace back to the prebiotic chemistry of early Earth. In this study, we present an innovative platform for antiviral exploration inspired by this primordial ...
Maria Grazia Martina +10 more
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