Results 51 to 60 of about 2,320,526 (267)

Electrostatic activation of prebiotic chemistry in substellar atmospheres [PDF]

open access: yes, 2014
Charged dust grains in the atmospheres of exoplanets may play a key role in the formation of prebiotic molecules, necessary to the origin of life. Dust grains submerged in an atmospheric plasma become negatively charged and attract a flux of ions that ...
Stark, Craig Ronald   +7 more
core   +1 more source

Did minerals perform prebiotic combinatorial chemistry? [PDF]

open access: yes, 1996
It has long been suspected that mineral surfaces may have been important in prebiotic chemistry. The recent demonstrations of extended oligomerization of nucleotides, amino acids and carbohydrates on mineral surfaces add support to the potential ...
Schwartz, Alan W., Schwartz, A.W.
core   +1 more source

Thermally Accessible Prebiotic Pathways for Forming RNA and Protein Precursors [PDF]

open access: yes, 2022
The search for prebiotic chemical pathways to biologically relevant molecules is a long- standing puzzle that has generated a menagerie of competing hypotheses with limited experimental prospects for falsification.
Qiyuan, Zhao   +2 more
core   +2 more sources

Spontaneous formation and base pairing of plausible prebiotic nucleotides in water

open access: yesNature Communications, 2016
One of the questions for prebiotic chemistry is the formation of complementary base pairing systems. Here, the authors show that plausible two prebiotic heterocycles can form glycosidic bonds with ribose in water and that these spontaneously base-pair in
Brian J. Cafferty   +4 more
doaj   +1 more source

Radicals in prebiotic chemistry

open access: yesPure and Applied Chemistry, 2020
Abstract Radical chemistry is tightly interwoven in proposed prebiotic synthetic pathways, reaction networks and geochemical scenarios that have helped shape our understanding of how life could have originated. Gas-phase prebiotic reactions involving electric discharge, vapour ablation by asteroidal and cometary impacts as well as ...
Renee W. J. Lim, Albert C. Fahrenbach
openaire   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

open access: yesAngewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec   +3 more
wiley   +2 more sources

Abiotic and prebiotic phosphorus chemistry [PDF]

open access: yes, 2011
The chief obstacle to understand the metabolic origin of life or RNA-based life is to identify a plausible mechanism for overcoming the clutter wrought by abiotic chemistry.
Micheletti, Gabriele <1977>
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

prebiotic phosphorus chemistry reconsidered

open access: yesOrigins of life and evolution of the biosphere, 1997
The available evidence indicates that the origin of life on Earth certainly occurred earlier than 3.5 billion years ago and perhaps substantially earlier. The time available for the chemical evolution which must have preceded this event is more difficult to estimate.
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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