Results 61 to 70 of about 2,831,810 (265)

Sulfur Amino Acids: From Prebiotic Chemistry to Biology and Vice Versa

open access: yes, 2021
International audienceTwo sulfur-containing amino acids are included in the list of the 20 classical protein amino acids. A methionine residue is introduced at the start of the synthesis of all current proteins.
Youssef-Saliba, Sparta, Vallée, Yannick
core   +2 more sources

A Model Study on the Dynamics of the Amino Acid Content in Micrometeoroids during Atmospheric Entry

open access: yesChemistry, 2020
A model for the survival of the amino acid content in micrometeorites and its possible transformations upon atmospheric entry is described. Since any organic species released in the atmosphere at high altitudes would exhibit a limited lifetime with ...
Carlo Canepa
doaj   +1 more source

Abiotic and prebiotic phosphorus chemistry [PDF]

open access: yes, 2011
The chief obstacle to understand the metabolic origin of life or RNA-based life is to identify a plausible mechanism for overcoming the clutter wrought by abiotic chemistry.
Micheletti, Gabriele <1977>
core   +1 more source

A prebiotic precursor to Life’s phosphate transfer system with an ATP analogue and histidyl peptide organocatalysts [PDF]

open access: yes, 2023
Biochemistry is dependent upon enzyme catalysts accelerating key reactions. At the origin of life, prebiotic chemistry must have incorporated catalytic reactions.
Iris B. A., Smokers   +4 more
core   +2 more sources

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

open access: yesAdvanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu   +10 more
wiley   +1 more source

Strands in a Web: Free Energies of Select Prebiotic Reactions with Sugars, Nitriles and Azoles

open access: yesLife
Using computational chemistry, we determined the free energy changes for the reactions of C2 and C3 sugars with HCN and NH2CN to form amino acids and azoles respectively.
Jeremy Kua, Alexandra N. Mateescu
doaj   +1 more source

Chemical Diversity of Metal Sulfide Minerals and Its Implications for the Origin of Life

open access: yesLife, 2018
Prebiotic organic synthesis catalyzed by Earth-abundant metal sulfides is a key process for understanding the evolution of biochemistry from inorganic molecules, yet the catalytic functions of sulfides have remained poorly explored in the context of the ...
Yamei Li, Norio Kitadai, Ryuhei Nakamura
doaj   +1 more source

Open questions in understanding life’s origins

open access: yesCommunications Chemistry, 2021
The chemical space of prebiotic chemistry is extremely large, while extant biochemistry uses only a few thousand interconnected molecules. Here we discuss how the connection between these two regimes can be investigated, and explore major outstanding ...
Christopher J. Butch   +3 more
doaj   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy