Results 61 to 70 of about 1,239,816 (243)
DiagnosticsBackground/Objectives: Accurate full-arch implant impressions are essential for predictable digital prosthodontics, yet the performance of different intraoral scanners (IOSs) remains variable.
Tareq Hajaj +9 more
doaj +1 more source
Particle determination of red soils using micro-pipette method
浙江大学学报. 农业与生命科学版, 2001 It was concluded from the results on a wide range texture of soils that particle composition of red soils could be analyzed effectively with a micro-pipette method (using 4.00 g soil and sampling 5 mL suspension) that have low coefficient of variation ...
ZHANG Ming-kui, JIANG Hong
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Study on GPS orientation experiment and method of improving location precision
浙江大学学报. 农业与生命科学版, 2004 Several orientation experiments with three different types of four GPS receivers were conducted which included single point orientation experiment and dynamic area measurement experiment.
YU Hai-hong, CHEN Su-shan, HE Yong
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Many Roles of Precision in Action
EntropyActive inference describes (Bayes-optimal) behaviour as being motivated by the minimisation of surprise of one’s sensory observations, through the optimisation of a generative model (of the hidden causes of one’s sensory data) in the brain. One of active
Jakub Limanowski +3 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Frontiers in Psychology, 2019 Originally, the stereotype threat effect – poorer performance due to a fear of fulfilling a negative stereotype about one’s group – was demonstrated for cognitive tasks (e.g. Steele and Aronson, 1995, or Steele, 1997).
Hilmar Grabow, Melanie Kühl
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source