Results 71 to 80 of about 1,239,816 (243)

Early detection and classification of Alzheimer’s disease through data fusion of MRI and DTI images using the YOLOv11 neural network

Frontiers in Neuroscience
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide, affecting over 55 million people globally, with numbers expected to rise dramatically.
Wided Hechkel, Abdelhamid Helali
doaj   +1 more source

ARTIFICIAL INTELLIGENCE IN BUSINESS OPERATIONS: EXPLORING PRODUCTIVITY AND ACCEPTANCE [PDF]

Annals of the University of Oradea: Economic Science
This paper will provide information on the impact of AI in daily life and work-related activities.Today, AI functionalities could nowadays transform businesses, playing a critical role in enhancing and improving decisions.
Ioana CIOFU, Giulia KONDORT, Stefana POP, Roxana CIOC   +3 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Performance Evaluation of a B-type Natriuretic Peptide Assay Using the Alinity i Analyzer

Korean Journal of Clinical Laboratory Science
B-type natriuretic peptide (BNP) is a crucial cardiac biomarker secreted from the ventricles in response to volume and pressure overload that is used widely in the diagnosis, prognosis, and risk assessments of heart failure.
Jae Yoon LEE, Chan Kyu KIM, Gi Yeong KIM, Kyung Sook CHOI, Ho Keun CHOI   +4 more
doaj   +1 more source

Comparative analysis of Access PCT and Elecsys BRAHMS PCT assays for procalcitonin measurements [PDF]

Kosin Medical Journal
Background Procalcitonin (PCT) is a crucial biomarker for diagnosing sepsis and managing antibiotic therapy. This study evaluated the analytical performance and comparability of the Access PCT and Elecsys BRAHMS PCT assays.
Hyunji Choi, Sang-Shin Lee, Hyunyong Hwang   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Analytical and Diagnostic Performance of a Dual‐Target Blood Detection Test for Hepatocellular Carcinoma

Cancer Reports
Background Surveillance approaches with high sensitivity and specificity for hepatocellular carcinoma (HCC) are still urgently needed. Previous studies have shown that methylation of GNB4 and Riplet can effectively diagnose HCC.
Qiankun Yang, Lanlan Dong, Lianglu Zhang, Wei Zhang, Yan Zhang, Yue Huang, Huifang Jin, Hao Yang, Xing Liu, Yanteng Zhao   +9 more
doaj   +1 more source

Nicholaus de Heybech of Erfurt, Table Maker and Copyist

Aestimatio
: Nicholaus de Heybech (fl. 1384–1394) is the author of a clever and compact solution to a major challenge for medieval astronomers: finding the time from mean to true syzygy. His table and associated canon for that purpose are now found in 30 manuscript
José Chabás, Bernard R. Goldstein
doaj   +1 more source