Results 91 to 100 of about 4,218,282 (383)

Precision medicine in mood disorders

PCN Reports, 2022
The choice of the most appropriate psychoactive medication for each of our patients is always a challenge. We can use more than 100 psychoactive drugs in the treatment of mood disorders, which can be prescribed either alone or in combination.
Alessandro Serretti
doaj   +1 more source

Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation

European Journal of Medical Research
This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and pharmaceuticals, opening up exciting therapeutic possibilities.
Shivang Dhoundiyal, Shriyansh Srivastava, Sachin Kumar, Gaaminepreet Singh, Sumel Ashique, Radheshyam Pal, Neeraj Mishra, F. Taghizadeh-Hesary   +7 more
semanticscholar   +1 more source

Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis [PDF]

, 2016
: This paper presents a review of the importance and role of precision medicine and molecular imaging technologies in cancer diagnosis with therapeutics and diagnostics purposes.
Alipour, Zeinab, Assadi, Majid, Ghasemi, Mojtaba, Nabipour, Iraj, Omrani, Abdolmajid   +4 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

iBiopsy® for Precision Medicine

European Medical Journal, 2018
A high-throughput artificial intelligence-powered image-based phenotyping platform, iBiopsy® (Median Technologies, Valbonne, France), which aims to improve precision medicine, is discussed in the presented review.
Johan Brag, Michaël Auffret, Corinne Ramos,, Yan Liu, Pierre Baudot   +4 more
doaj  

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J, Kato, Shumei, Kurzrock, Razelle, Lippman, Scott M   +3 more
core  

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs [PDF]

, 2019
We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied psychiatric patients, a high risk
Jones, T., Judd, S., Khan, F., Kurian, S. M., Le-Niculescu, H., Levey, D. F., McCormick, M.A., Niculescu, A. B., Rogers, J., Roseberry, K., Soe, K. C., Wessel, A. R., White, F. A., Williams, A.   +13 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Tribulations and future opportunities for artificial intelligence in precision medicine

Journal of Translational Medicine
Upon a diagnosis, the clinical team faces two main questions: what treatment, and at what dose? Clinical trials' results provide the basis for guidance and support for official protocols that clinicians use to base their decisions.
Claudio Carini, A. Seyhan
semanticscholar   +1 more source

Precision medicine for suicidality: from universality to subtypes and personalization [PDF]

, 2017
Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders.
Ballew, A, Dainton, H L, Gelbart, T, Graham, D L, Jones, T J, Kurian, S M, Le-Niculescu, H, Levey, D F, Niculescu, A B, Niculescu, E M, Niezer, J O, Phalen, P L, Roseberry, K, Salomon, D R, Sandusky, G E, Schork, N J, Shekhar, A, Venugopal, V, Williams, A, Yard, M   +19 more
core   +1 more source