Results 91 to 100 of about 1,104,938 (358)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Precision Medicine in Cardiovascular Diseases

open access: yesCardiovascular Innovations and Applications, 2017
Since President Obama announced the Precision Medicine Initiative in the United States, more and more attention has been paid to precision medicine. However, clinicians have already used it to treat conditions such as cancer. Many cardiovascular diseases
Yan Liu, Jie Du
doaj   +1 more source

SAFS: A Deep Feature Selection Approach for Precision Medicine

open access: yes, 2017
In this paper, we propose a new deep feature selection method based on deep architecture. Our method uses stacked auto-encoders for feature representation in higher-level abstraction.
Levy, Phillip   +4 more
core   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Building a Controlled Vocabulary for Standardizing Precision Medicine Terms [PDF]

open access: yesarXiv, 2018
Rapid advances of technology and development of research in precision medicine domain have led to the production of different types of biomedical data. Standard medical vocabularies were shown to be limited in dealing with such heterogeneous data and consequently, new controlled vocabulary for data integration and normalization has been proposed.
arxiv  

Dynamic treatment regime characterization via value function surrogate with an application to partial compliance [PDF]

open access: yesarXiv, 2022
Precision medicine is a promising framework for generating evidence to improve health and health care. Yet, a gap persists between the ever-growing number of statistical precision medicine strategies for evidence generation and implementation in real world clinical settings, and the strategies for closing this gap will likely be context dependent.
arxiv  

Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis [PDF]

open access: yes, 2016
: This paper presents a review of the importance and role of precision medicine and molecular imaging technologies in cancer diagnosis with therapeutics and diagnostics purposes.
Alipour, Zeinab   +4 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Big Data for Precision Medicine

open access: yesEngineering, 2015
This article focuses on the potential impact of big data analysis to improve health, prevent and detect disease at an earlier stage, and personalize interventions.
Daniel Richard Leff, Guang-Zhong Yang
doaj   +1 more source

Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]

open access: yes, 2017
In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
core   +1 more source

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