Results 241 to 250 of about 8,733,364 (311)

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

open access: yesAdvanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong   +11 more
wiley   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Advances in diabetic foot ulcer management: a narrative review of novel antibiotics, nanotechnology, and regenerative therapeutics. [PDF]

open access: yesFront Microbiol
Saleem M   +10 more
europepmc   +1 more source

Preclinical evaluation of AHR-1118, a potential antidepressant drug.

open access: yesCurrent therapeutic research, clinical and experimental, 1970
D N, Johnson, W H, Funderburk, J W, Ward
openaire   +1 more source

The past, the present, and the future of preclinical mouse models for Alzheimer's disease and related dementias. [PDF]

open access: yesAlzheimers Dement
Oblak AL   +7 more
europepmc   +1 more source

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