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Blood-Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems. [PDF]
MedComm (2020)He Y +10 more
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Preclinical activity of SHR-A1921, a novel antibody-drug conjugate targeting trophoblast cell-surface antigen2 (Trop-2) in prostate cancer. [PDF]
Front PharmacolWang B +6 more
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Interpreting Reduced Postoperative hs-cTnT After Intraoperative Esketamine: Methodological Considerations [Letter]. [PDF]
Drug Des Devel TherLu CW, Chang KC.
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Integrating New Approach Methodologies (NAMs) into Preclinical Regulatory Evaluation of Oncology Drugs. [PDF]
Biomimetics (Basel)Mirlohi MS +3 more
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Moving beyond shock: Rich-lean transition procedures as a modern approach to anxiolytic screening. [PDF]
J Pharmacol Exp TherRough MI, Kratzenberg JL.
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Preclinical evaluation of UC781 microbicide vaginal drug delivery
Drug Delivery and Translational Research, 2011UC781 is a potent nonnucleoside reverse transcriptase inhibitor being investigated as a potential microbicide to prevent transmission of HIV-1 both vaginally and rectally. This study was designed to investigate the in vitro drug release, in vitro permeability/safety, and in vivo pharmacokinetics in rabbits of a vaginal gel prepared with micronized or ...
Meredith R, Clark +3 more
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Bupropion-induced convulsions: Preclinical evaluation of antiepileptic drugs
Epilepsy Research, 2005Bupropion, a unique, non-nicotine smoking cessation aid and an effective antidepressant, is well known to produce seizures following overdosing in humans. However, the experimental background for the usefulness of antiepileptic drugs in the protection against bupropion-induced convulsions has not been established yet.
Piotr, Tutka +4 more
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