Results 261 to 270 of about 307,974 (304)

Treatment of schizophrenia: A clinical and preclinical evaluation of neuroleptic drugs

Pharmacology & Therapeutics, 1993
Forty years after the first clinical report on the effectiveness of chlorpromazine in psychiatric patients, neuroleptic drugs are still the most widely used drugs in the treatment of schizophrenia. Indeed, there are no other drugs which have proven to be as effective in the treatment of this severe psychiatric disorder.
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Preclinical evaluation of drug effects on testicular functions

Pharmacology & Therapeutics, 1979
F, Neumann, B, Schenck
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Preclinical Evaluation of Neuraxial Drugs for Safety

2023
Tony L. Yaksh, Robert B. Boyd, Orion Paul Keifer   +2 more
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Evaluation of Antiseptic Drug Candidate Pyridosept in Preclinical in Vitro Studies

Current Medicinal Chemistry
Introduction: This work provides preclinical in vitro studies of an innovative antimicrobial agent named pyridosept, belonging to the quaternary bis-ammonium salts and synthesized on the base of pyridoxine. Since the wide spread of pathogens with tolerance to both antibiotics and antiseptics challenges the ...
Renata Kazakova, Alfiya Iksanova, Mariya Agafonova, Anna Lubina, Elena Bulatova, Elena Nikitina, Svetlana Lisovskaya, Airat Kayumov, Oxana Bondar, Albina Malanyeva, Olga Vasileva, Marina Zeldi, Alina Gatina, Sergei Koshkin, Natalia Komcharova, Yulia Konyakhina, Kseniia Titova, Aleksandr Sergeev, Sergey Sapozhnikov, Nikita Shtyrlin, Yurii Shtyrlin   +20 more
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Human malignant melanoma: preclinical and clinical drug evaluation.

Behring Institute Mitteilungen, 1984
A panel of 17 melanoma xenograft lines was exposed to various DNA reactive agents. Growth delay values were calculated from tumor volume responses of xenograft bearing mice and correlated with donor patient's response as determined by standard clinical criteria.
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Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials

Nature Reviews Drug Discovery, 2021
E Elizabeth Patton, Leonard I Zon, David Langenau   +2 more
exaly  

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Chiara Corti   +2 more
exaly  

A Postgraduate Course in Preclinical Drug Evaluation

Therapies, 2004
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Harnessing the predictive power of preclinical models for oncology drug development

Nature Reviews Drug Discovery, 2021
Alexander Honkala, Shivaani Kummar, Melissa R Junttila   +2 more
exaly  

Preclinical evaluation of anti-CD269 antibody–drug conjugates

European Journal of Cancer, 2016
A. Palfi, M. Kulke, C. Mueller, C. Lutz, A. Pahl, T. Hechler   +5 more
openaire   +1 more source