Results 271 to 280 of about 307,974 (304)

[Preclinical/toxicologic evaluation of drugs].

Ugeskrift for laeger, 1999
Knudsen, Lisbeth E., Spindler, Per, Renneberg, Jan   +2 more
openaire   +1 more source

Preclinical Drug Safety Evaluation

2011
openaire   +1 more source

Angiogenesis Inhibitors: Current Strategies and Future Prospects

Ca-A Cancer Journal for Clinicians, 2010
Kristina M Cook, William D Figg
exaly  

Preclinical Drug Safety Evaluation

2008
openaire   +1 more source

Mitigating risk in academic preclinical drug discovery

Nature Reviews Drug Discovery, 2015
Jayme L Dahlin, James Inglese, Michael A Walters   +2 more
exaly  

Preclinical Drug Safety Evaluation

2016
openaire   +1 more source

Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Nature Reviews Drug Discovery, 2019
Richard J Weaver, Amy E Chadwick, Christopher E Goldring   +2 more
exaly  

Prediction of antibiotic resistance: time for a new preclinical paradigm?

Nature Reviews Microbiology, 2017
Morten O A Sommer, Christian Munck, Dan Andersson   +2 more
exaly  

[Preclinical evaluation of anticancer drugs: a model remaining a model!].

Bulletin du cancer, 1998
Two criteria are firstly used in the selection of new anticancer agents:--originality of the mechanism of action and significant experimental antitumor activity in an in vivo animal model. Murine tumors grafted in syngenic mice and human tumor xenografts implanted in nude mice are old models which continue to be widely used.
openaire   +1 more source

The global preclinical antibacterial pipeline

Nature Reviews Microbiology, 2019
Ursula Theuretzbacher, Kevin Outterson, Aleks Engel   +2 more
exaly