Results 281 to 290 of about 1,044,728 (382)

MWB_Analyzer: An Automated Embedded System for Real-Time Quantitative Analysis of Morphine Withdrawal Behaviors in Rodents. [PDF]

Toxics
Zhang M, Li Q, Li S, Sun B, Wu Z, Liu J, Geng X, Chen F.   +7 more
europepmc   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

From toxicity assessment to adaptive safety care: implementing comprehensive fast-track safety evaluation for anticancer drug development. [PDF]

ESMO Open
Champiat S, Ouali K, Laparra A, Charalambous A, Di Palma M, Jordan K, Massard C, Aapro M, Scotte F.   +8 more
europepmc   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

Advanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh, Jae‐Hun Kim, Sunwoo Lee, Jin‐Hyung Shim, Won‐Soo Yun, Songwan Jin   +5 more
wiley   +1 more source

Closing the Evidence Gap: Retrospective and Prospective Strategies to Advance Aripiprazole's Potential Benefits in Patients With Cancer. [PDF]

Pharmacol Res Perspect
Gkrinia EMM, Golčić M, Belančić A.
europepmc   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source

Drug repurposing in traditional Chinese medicine: from empirical wisdom to modern therapeutic strategies. [PDF]

Front Pharmacol
Wu Y, Huang J, Guo J, Lian W, Suo M.
europepmc   +1 more source

Table S3 from Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach

Courtney R. Schott, Amanda Koehne, Leanne C. Sayles, Elizabeth P. Young, Cuyler Luck, Katharine Yu, Alex G. Lee, Marcus R. Breese, Stanley G. Leung, Hang Xu, Avanthi Tayi Shah, Heng-Yi Liu, Aviv Spillinger, Inge H. Behroozfard, Kieren D. Marini, Phuong Dinh, María V. Pons Ventura, Emma N. Vanderboon, Florette K. Hazard, Soo‐Jin Cho, Raffi S. Avedian, David G. Mohler, Melissa N. Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, E. Alejandro Sweet‐Cordero   +26 more
openalex   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development. [PDF]

Int J Toxicol
Pierson JB, Bahinski A, Berridge B, Bramham D, Bourcier T, Chaudhary KW, Eldridge S, Kanda Y, Mattes WB, Oliphant J, Pang L, Savtchenko A, Siegel J, Simpson N, Tu C, Wange R, Wu JC, Yang X.   +17 more
europepmc   +1 more source