Results 291 to 300 of about 303,204 (352)

Wheatgrass-Tulsi Self-Emulsifying Drug Delivery System (WT-SEDDS): Preclinical Evaluation Of Synergistic Anticancer Activity

Pravin Badhe
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Porcine Corneal Models as Translational Platforms for Innovative Therapies: Current Insights and Future Directions. [PDF]

J Funct Biomater
Nápoles P, Faria M, Campos EJ.
europepmc   +1 more source

Innovation Policy and the Economy, Volume 6 [PDF]

Adrian H. B. Gottschalk, Ernst R. Berndt, Matthew W. Strobeck   +2 more
core  

Engineering exosomes for Alzheimer's disease: Multi-target therapeutic strategies from pathogenesis to clinical translation. [PDF]

Clin Transl Med
Zhang Y, Li Z, Guan H, Qiu Z, Zou C.
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Materials and Methods from Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for treatment of Nectin-4-expressing Cancers

Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Long Yin, Fei Mei, Huikai Zhu, Zhenzhen Wang, Hui Xu, Yuxia Cao, Xiaowei Sun, Xiaohong Xu, Jianjun Bi, Jin Wang, Lanping Ma, Xin Wang, Lin Chen, Yongliang Zhang, Xiaowei Cen, Xi Zhu, Liguang Lou, Datao Liu, Xiaoding Tan, Jinliang Yang, Tao Meng, Jingkang Shen   +26 more
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Preclinical evaluation of UC781 microbicide vaginal drug delivery

Drug Delivery and Translational Research, 2011
UC781 is a potent nonnucleoside reverse transcriptase inhibitor being investigated as a potential microbicide to prevent transmission of HIV-1 both vaginally and rectally. This study was designed to investigate the in vitro drug release, in vitro permeability/safety, and in vivo pharmacokinetics in rabbits of a vaginal gel prepared with micronized or ...
Meredith R, Clark, Timothy J, McCormick, Gustavo F, Doncel, David R, Friend   +3 more
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Bupropion-induced convulsions: Preclinical evaluation of antiepileptic drugs

Epilepsy Research, 2005
Bupropion, a unique, non-nicotine smoking cessation aid and an effective antidepressant, is well known to produce seizures following overdosing in humans. However, the experimental background for the usefulness of antiepileptic drugs in the protection against bupropion-induced convulsions has not been established yet.
Piotr, Tutka, Tomasz, Mróz, Katarzyna, Klucha, Małgorzata, Piekarczyk, Marian, Wielosz   +4 more
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Evaluation of Nanoparticle Drug-Delivery Systems used in Preclinical Studies

Therapeutic Delivery, 2021
Multifunctional nanoparticles have been identified as a promising drug-delivery system for sustainable drug release. The structural and size tunability and disease-targeting ability of nanoparticles have made them more suitable for multiple drug loading and delivery, thereby enhancing therapeutic results through synergistic effects.
Nagaraja Sreeharsha, Nataraj Chitrapriya, Yoon Jung Jang, Vanaja Kenchappa   +3 more
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Preclinical evaluation of behavioral deficits following hypnotic drug treatment

Pharmacology Biochemistry and Behavior, 1986
Most hypnotic medications result in performance decrements, or "hangover effects," the morning after bedtime ingestion. However, the severity of hangover effects with new compounds is difficult to predict prior to clinical trials. This paper describes a preclinical procedure that is predictive of human hangover effects following bedtime ingestion of ...
J M, Halperin, J, Canon, L C, Iorio
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