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Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis [PDF]
Neuro-Oncology Advances, 2021 Brain metastasis (BM) is a major cause of cancer patient morbidity. Clinical magnetic resonance imaging (MRI) and positron emission tomography (PET) represent important resources to assess tumor progression and treatment responses.
Synnøve Nymark Aasen +2 more
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The Basics of Visualizing, Analyzing, and Reporting Preclinical PET/CT Imaging Data
Methods in Molecular Biology, 2023 Positron emission tomography (PET) has transformed medical imaging, and while first developed and applied to the human setting, it has found widespread application at the preclinical level over the past two decades.
Christopher Cawthorne +2 more
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Applications for Preclinical PET/MRI
Seminars in Nuclear Medicine, 2013Currently, the combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its emerging clinical applications but also in the preclinical field. Several prototypes based on several different types of PET detector technology have been developed in recent ...
Martin S, Judenhofer, Simon R, Cherry
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SimPET: a Preclinical PET Insert for Simultaneous PET/MR Imaging
Molecular Imaging and Biology, 2020SimPET/M7 system is a small-animal dedicated simultaneous positron emission tomography and magnetic resonance imaging (PET/MRI) scanner. The SimPET insert has been upgraded from its prototype with a focus on count rate performance and sensitivity. The M7 scanner is a 1-T permanent magnet-based compact MRI system without any cryogens.
Jeong-Whan, Son +6 more
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Preclinical Studies with Small Animal PET
PET Clinics, 2011Because no effective cures are available for cutaneous malignant melanoma, early diagnosis and accurate staging are of the utmost importance in increasing patient survival. Fluorodeoxyglucose positron emission tomography (PET)/computed tomography is a functional imaging technique that has contributed to ameliorating surveillance of patients with ...
NANNI, CRISTINA, FANTI, STEFANO
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Current Trends in Preclinical PET System Design
PET Clinics, 2007PET is used in laboratory small-animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease, and neurologic disorders in living small-animal models of disease. The current and next generation of PET molecular imaging probes, assays, and imaging systems still have substantial room to improve ...
Craig S, Levin, Habib, Zaidi
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Preclinical Studies of SPECT and PET Tracers for NET
PET Clinics, 2014Radiolabeled somatostatin analogues are routinely used for the detection of neuroendocrine tumors (NETs), exploiting the expression of somatostatin-receptor subtypes on the cell membrane. Because of the heterogeneity of the origin of these tumors, the performance of radiolabeled somatostatin analogues in certain types of NETs is limited due to the low ...
Brom, M. +6 more
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Evaluation of the spline reconstruction technique for preclinical PET imaging
Computer Methods and Programs in Biomedicine, 2022The Spline Reconstruction Technique (SRT) is a fast algorithm based on a novel numerical implementation of an analytic representation of the inverse Radon transform. The purpose of this study is to provide a comparison between SRT, Filtered Back-Projection (FBP), Ordered Subset Expectation Maximization 2D (2D-OSEM), and the Tera-Tomo 3D algorithm ...
Alexandros Vrachliotis +7 more
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Detection of preclinical Parkinson's disease with PET
Neurology, 1991Putamen 18F-dopa uptake of patients with Parkinson's disease (PD) is reduced by at least 35% at onset of symptoms; therefore, positron-emission tomography (PET) can be used to detect preclinical disease in clinically unaffected twins and relatives of patients with PD. Three out of 6 monozygotic and 2 out of 3 dizygotic unaffected PD co-twins have shown
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