Results 141 to 150 of about 9,971 (304)

Pipelined Space-Time Krylov Method with Preconditioning: A Parallel-in-Time Algorithm for Biot’s Quasi-Static Poroelasticity

Mathematics
This paper presents a preconditioner-based parallel-in-time (PinT) method for solving the quasi-static Biot’s consolidation model in poroelasticity, a problem characterized by stiff coupling and saddle-point structures.
Guoliang Ju, Xin Xia, Zeyuan Zhou, Yan Gao, Huipeng Gu, Jiake Tian, Longfeng Nie, Xucong Wang, Wei Xing   +8 more
doaj   +1 more source

Physically-based preconditioner for the WCIP

, 2012
International audienceA physically-based preconditioner for the 1d and 2d Wave Concept Iterative Procedure is introduced in this paper.
N. Raveu, Perrussel, Ronan, J.-R. Poirier, Vincent, Julien, Giraud, Luc, Raveu, Nathalie, J. Vincent, Poirier, Jean-René, L. Giraud, R. Perrussel   +9 more
core   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

A comparison of deflation and the balancing Neumann-Neumann preconditioner

, 2004
In this paper we compare various preconditioners for the numerical solution of partial differential equations. We compare the well-known balancing Neumann Neumann preconditioner used in domain decomposition methods with a so-called deflation ...
Vuik, C. (author), Nabben, R. (author), R. Nabben, C. Vuik   +3 more
core  

Accelerated Discovery of Earth‐Abundant Oxygen Evolution Catalysts Through Surface‐Informed Active Learning

Advanced Science, EarlyView.
A surface‐informed active learning framework integrated with density functional theory enables resource efficient screening of the NiCoFe ternary composition space. Experimental validation identifies Ni55Co10Fe35 as the optimal composition, exhibiting favorable oxygen evolution reaction kinetics.
Hayun Jeon, Minhee Park, Won Bo Lee, Seyoung Park, YongJoo Kim, Sungwook Mhin   +5 more
wiley   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Phosphonium Ionic Liquids for Electrochemical Energy Storage: Structure–Property–Interphase Relationships and Design Rule

Advanced Science, EarlyView.
Phosphonium ionic liquids offer a versatile platform for safer and more durable energy storage. This Review connects cation–anion structure with solvation, ion transport, electrochemical stability, and interphase formation across diverse battery chemistries.
Amir Haghipour, Ishanka Thennakoon, Aishwaryaba Jadeja, Daniel Rauber, Markus Gallei, Rolf Hempelmann, Sangwon Kim, Jungtae Kim   +7 more
wiley   +1 more source