Results 131 to 140 of about 9,757 (303)
Advanced Science, EarlyView.Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
A Randomized Algorithm for Preconditioner Selection [PDF]
, 2019 The task of choosing a preconditioner $\boldsymbol{M}$ to use when solving a linear system $\boldsymbol{Ax}=\boldsymbol{b}$ with iterative methods is difficult.
Gu, Weiqing, DiPaolo, Conner
core
Advanced Science, EarlyView.This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Mesoporous‐Shell Monolayer Plasmonic Architecture Enables Quantitative and Decision‐Guided SERS
Advanced Science, EarlyView.Mesoporous‐shell‐regulated molecular transport combined with monolayer hotspot determinism transforms surface‐enhanced Raman spectroscopy (SERS) from ultrasensitive detection into quantitative and decision‐guided molecular sensing. ABSTRACT Quantitative surface‐enhanced Raman spectroscopy (SERS) has long been impeded by stochastic hotspot formation ...
Guangyao Huang +9 more
wiley +1 more source
, 2019 International audienceIn this paper, we propose a stabilized dimensional factorization (SDF) preconditioner for saddle point problems arising from the discretization of Navier-Stokes equations. The idea is based on regularization, block factorization and
Xu, Yingxiang +2 more
core +1 more source
Advanced Science, EarlyView.Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang +12 more
wiley +1 more source
A nearly optimal preconditioner for the Navier-Stokes equations [PDF]
, 1999 We present a preconditioner for the linearised Navier-Stokes equations which is based on the combination of fast transform approximation of an advection diffusion problem together with the recently introduced '$BFB^{T}$' preconditioner of Elman (SIAM J ...
Wathen, A. J. +1 more
core
An algebraic multifrontal preconditioner that exploits the low-rank property
, 2016 We present an algebraic structured preconditioner for the iterative solution of large sparse linear systems. The preconditioner is based on a multifrontal variant of sparse LU factorization used with nested dissection ordering. Multifrontal factorization
Napov, Artem +3 more
core +1 more source
Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
wiley +1 more source
MathematicsThis paper presents a preconditioner-based parallel-in-time (PinT) method for solving the quasi-static Biot’s consolidation model in poroelasticity, a problem characterized by stiff coupling and saddle-point structures.
Guoliang Ju +8 more
doaj +1 more source