Results 131 to 140 of about 22,776 (283)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

The Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Quantum computing and preconditioners for hydrological linear systems. [PDF]

Sci Rep, 2022
Golden J, O'Malley D, Viswanathan H.
europepmc   +1 more source

Continuous Sewing Machine‐Like Suture Provides Higher Failure and Yield Load Compared to Traditional Techniques for Meniscal Root Repair in a Biomechanical Porcine Model

Arthroscopy, EarlyView.
Purpose To evaluate the biomechanical performance of the sewing machine‐like suture (SMS) technique against three established techniques (two cinch‐loop (TCL), modified Mason‐Allen (MMA), and double Mason‐Allen (DMA)) for transtibial pull‐out repair of posterior medial meniscal root tear (PMMRT) in a porcine model.
Yizhong Peng, Wenbo Yang, Yi Li, Chunqing Meng, Hong Wang, Wei Huang   +5 more
wiley   +1 more source

Anterior Cruciate Ligament Reconstruction Using the Tape‐Active Reconstruction System With Semitendinosus Graft: A Primary Load‐Bearing Construct

Arthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament reconstruction is a widely performed orthopaedic procedure; however, early graft elongation and loss of tension remain significant biomechanical challenges, particularly with the use of soft tissue autografts. In this technical note, the tape‐active reconstruction system is described as an augmentation technique in ...
Ahmet Emin Okutan, Lokman Kehribar
wiley   +1 more source

Generalizable preconditioning strategies for MAP PET reconstruction using Poisson likelihood. [PDF]

Front Nucl Med
Colombo MN, Paganoni M, Presotto L.
europepmc   +1 more source

Preconditioner circuit analysis

, 2011
Voltages up to 10,000 volts or higher must be attenuated and measured to provide control feedback for many applications like medium voltage generators or pulsed power systems. How these medium voltage signals can be conditioned so that they can be input to analog control circuits or analog-to-digital converters is the focus of this thesis.
openaire   +1 more source

From cramming to binge‐watching: Integrating documentary‐based assessment into a pharmacology and toxicology curriculum—a qualitative study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi, Heleen van der Sijs, Floor van Rosse   +2 more
wiley   +1 more source

Fast Numerical Solvers for Parameter Identification Problems in Mathematical Biology. [PDF]

J Sci Comput
Benková K, Pearson JW, Ptashnyk M.
europepmc   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source