Results 131 to 140 of about 9,971 (304)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

A novel multigrid based preconditioner for heterogeneous Helmholtz problems

open access: yes, 2004
An iterative solution method, in the form of a preconditioner for a Krylov subspace method, is presented for the Helmholtz equation. The preconditioner is based on a Helmholtz type differential operator with a complex term.
Erlangga, Y.A. (author)   +2 more
core  

Mechanically Reprogrammed Coaxial Fibers for Multiphysics Transduction and Human‐Machine Interfaces

open access: yesAdvanced Science, EarlyView.
A continuously wet‐spun coaxial fiber is developed to combine stretchable conductivity, resistive sensing, and self‐powered triboelectric sensing in a single architecture. A mechanically reprogrammed dual‐network sheath stabilizes large deformation and improves signal reliability. These fibers can be woven into textile interfaces for multichannel touch
Xinyi Cao   +6 more
wiley   +1 more source

A robust parameterized enhanced shift-splitting preconditioner for three-by-three block saddle point problems

open access: yes
This paper proposes a new parameterized enhanced shift-splitting (PESS) preconditioner to solve the three-by-three block saddle point problem (SPP).
Ahmad, Sk. Safique, Khatun, Pinki
core   +1 more source

A polynomial preconditioner for block tridiagonal matrices

open access: yes, 1994
This paper is concerned with the solution of block tridiagonal linear systems by the preconditioned conjugate gradient (PCG) method. If we consider a block AGE splitting of the coefficient matrix, it is possible to derive an additive polynomial ...
V. RUGGIERO, GALLIGANI, Emanuele
core   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

An Inexact Balancing Preconditioner for Large-Scale Structural Analysis

open access: yes
The balancing domain decomposition (BDD) method is a well-known preconditioner due to its excellent convergence rate. The BDD method includes the Neumann-Neumann preconditioner and a coarse grid correction. Several studies have considered applications of
金山, 寛   +8 more
core   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

open access: yesAdvanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan   +13 more
wiley   +1 more source

A Fast Preconditioner For Helmholtz Equation

open access: yes, 2012
This monograph implements a fast preconditioner of Helmholtz Equation and a related GMRES iterative algorithm.
Deng, Xiaodi
core   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao   +7 more
wiley   +1 more source

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