Results 141 to 150 of about 46,756 (266)

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Tacrolimus (FK506) Attenuates Hepatic Ischemia-Reperfusion Injury via Oxidative Glutathione Metabolism and Suppression of Lipoxygenase-Mediated Cell Death. [PDF]

Antioxidants (Basel)
Drefs M, Schirren MJ, Koch DT, Jacobi SJ, Neuberger M, Holdt LM, Renz BW, Werner J, Guba MO, Koliogiannis D.   +9 more
europepmc   +1 more source

Anesthetic preconditioning as the alternative to ischemic preconditioning [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2006
Lange, Markus, Roewer, Norbert, Kehl, Franz   +2 more
openaire   +1 more source

Civilising pedagogies: An ethnography of instructional and regulative discourses in government schools in Delhi, India

British Educational Research Journal, EarlyView.
Abstract Over the years, surveys and data on learning outcomes have consistently shown inadequate levels of learning in schools in India, witnessing a further decline in recent years. Studies within the sociology of education have consistently highlighted the overarching role of class and caste on learning outcomes in schools. Neoliberal policy reforms
Akshita Rawat
wiley   +1 more source

Matrix-Free Inexact Preconditioning Techniques for Isogeometric Tensor-Product Discretizations. [PDF]

J Sci Comput
Mika MŁ, Hiemstra RR, Schillinger D.
europepmc   +1 more source

Making teaching more attractive: Promising evidence of impact from Australia

British Educational Research Journal, EarlyView.
Abstract Sustaining teaching as a respected and attractive profession is more critical than ever, particularly as teachers' work becomes increasingly shaped by standardisation and accountability—conditions that have shown minimal positive impact while eroding the professional agency essential to job satisfaction.
Jennifer M. Gore, Sally Patfield, Leanne Fray, Andrew Miller, Brooke Rosser, Matthew Harper   +5 more
wiley   +1 more source

Iron overload is associated with increased susceptibility to pulmonary Pythium insidiosum infection in mice. [PDF]

PLoS Negl Trop Dis
Zhu D, Yan L, Sun J, Chen S, Xi Y, Zhang K, Li M.   +6 more
europepmc   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang, Amin Javidanbardan, Ali Behboudi, Andrew L. Zydney   +3 more
wiley   +1 more source

dCA1 cells encode and update contextual place preference. [PDF]

Front Syst Neurosci
Choi K, Lim IE, Vats A, Tarver SM, Vaughn TB, Ogundele OM.   +5 more
europepmc   +1 more source

9. Preconditioning and Parallel Preconditioning [PDF]

, 1998
openaire   +1 more source