Results 141 to 150 of about 134,907 (287)

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Precondition [PDF]

, 2020
openaire   +1 more source

Civilising pedagogies: An ethnography of instructional and regulative discourses in government schools in Delhi, India

British Educational Research Journal, EarlyView.
Abstract Over the years, surveys and data on learning outcomes have consistently shown inadequate levels of learning in schools in India, witnessing a further decline in recent years. Studies within the sociology of education have consistently highlighted the overarching role of class and caste on learning outcomes in schools. Neoliberal policy reforms
Akshita Rawat
wiley   +1 more source

Photothermal preconditioning of platelet-rich plasma: An emerging regenerative strategy. [PDF]

Regen Ther
Sánchez-Vizcaíno Mengual E, Cordero L, Pinto H.   +2 more
europepmc   +1 more source

Making teaching more attractive: Promising evidence of impact from Australia

British Educational Research Journal, EarlyView.
Abstract Sustaining teaching as a respected and attractive profession is more critical than ever, particularly as teachers' work becomes increasingly shaped by standardisation and accountability—conditions that have shown minimal positive impact while eroding the professional agency essential to job satisfaction.
Jennifer M. Gore, Sally Patfield, Leanne Fray, Andrew Miller, Brooke Rosser, Matthew Harper   +5 more
wiley   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

Biological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson, Ellen Wohl, Laura L. Govers, Oscar Franken, Tjeerd J. Bouma, Han Olff, Britas Klemens Eriksson, Maryann S. Watson, Luísa M.S. Borges, Tjisse van der Heide   +9 more
wiley   +1 more source

Correction: Effect of exercise preconditioning on myocardial content of Sphingosine1-phosphate and its mechanism in rats after exhaustive exercise. [PDF]

PLoS One
Wei X, Yang W, Zhou J, Cao L, Jiang W.
europepmc   +1 more source

Charting the Course: Real‐World Application of Sustainability and Innovation Principles in the Portuguese Blue Economy Firms

Business Strategy and the Environment, EarlyView.
ABSTRACT The blue economy has emerged as a key sector for linking sustainability and innovation, yet existing research has largely overlooked how firms operationalize these processes in practice. This study addresses that gap by asking: How do Portuguese blue economy firms embed sustainability‐oriented innovation (SOI) into their strategies, and what ...
Jennifer Nicole Elston, Hugo Emanuel dos Reis Sales da Cruz Pinto, Carla Filipa Sequeira Valente Nogueira   +2 more
wiley   +1 more source

Comparison of the effects of direct and remote ischemic post and preconditioning in the kidney of young rats: histological and laboratory evaluation. [PDF]

Acta Cir Bras
Oliveira AHA, Paula DM, Serafini S, Tannuri U, Tannuri ACA.   +4 more
europepmc   +1 more source