Results 151 to 160 of about 80,518 (304)

Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming

Advanced Science, EarlyView.
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva, Virginia Marcia Concato‐Lopes, Fatima Bedier, Lauren Newman, Diana Kitka, Jamelle Brown, Blandine Victor, Minhyung Kim, Tatyana Vagner, Catherine Grasso, Dmitriy Sheyn, Sungyong You, Michael R. Freeman, Fayyaz S. Sutterwala, Helen S. Goodridge, Caroline Jefferies, Paola de Candia, Jlenia Guarnerio, Dolores Di Vizio   +18 more
wiley   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

Preconditioning Techniques in Krylov Subspace Methods

This study discusses preconditioning approaches to address large, sparse linear systems as well as Krylov subspace methods. Among others, computational fluid dynamics, structural analysis, and electromagnetic simulations use Krylov methods like the ...
Najm, Zina Jabbar
core   +1 more source

Reliable Evaluation of Na‐Ion Battery Materials: Eliminating Na‐Metal Distortions

Advanced Energy Materials, EarlyView.
Na metal is highly reactive in carbonate electrolytes, forming unstable interphases and triggering parasitic reactions that distort measurements and undermine reproducibility. To enable accurate evaluation of materials for Na‑ion batteries, this work suggests that NASICON‑type counter electrodes provide a practical and stable platform for distortion ...
Jinkwang Hwang, Shaoning Zhang, Seongjae Ko, Tomoki Takahashi, Kosei Araya, Duanfei Han, Masashi Okubo, Atsuo Yamada, Shinichi Komaba, Kazuhiko Matsumoto   +9 more
wiley   +1 more source

Hyperglycemia attenuates myocardial preconditioning of remifentanil

, 2012
BACKGROUND: Hyperglycemia attenuates cardioprotection by remifentanil-preconditioning in ischemia-reperfusion in vivo in diabetic rats. However, the effects of hyperglycemia in cultured ventricular myocytes remains unknown.
김소연, 황기철, 심연희, 곽영란   +3 more
core  

Estimation of Import Demand Functions of Two Key Food and Feed Commodities (Corn and Soybean) for India

Agribusiness, EarlyView.
ABSTRACT The derived demand for the increased demand for meat and dairy products is clearly observed in the fast‐paced growth of the Indian feed industry and its increased demand for agricultural commodities (e.g., corn, soybean, rice, wheat, broken rice, millet, etc.) as feed ingredients.
Dwiti Baruah Thapa, Sanjib Bhuyan, Kishor Goswami   +2 more
wiley   +1 more source

Hydration Behavior of Tricalcium Silicate in Seawater Relevant Salt Systems: A Hybrid Study with the Aid of Machine Learning

Advanced Intelligent Discovery, EarlyView.
The hydration behavior of C3S in seawater‐relevant solutions is studied based on experiments, boundary nucleation and growth (BNG) modeling, and machine learning. The main ions included in seawater modify hydration mechanisms, with MgCl2 showing the strongest acceleration effect at the same concentration.
Yanjie Sun, Chen Zhang, Ting Zhang, Mengze Hong, Peiliang Shen, Chi Sun Poon, Gang Li   +6 more
wiley   +1 more source

A Two‐Stage Characterization Pipeline and Open‐Source Framework for Reproducible Tactile Sensing

Advanced Intelligent Systems, EarlyView.
The same soft tactile sensor returns different numbers when embodied in different robots. This is an Embodiment Gap that no shared framework currently captures transparently. A two‐stage characterization pipeline, paired with a FAIR open‐source digital datasheet, decouples intrinsic sensor behavior from embodiment effects and condenses cross‐laboratory
Matteo Lo Preti, Weng Buxiu, Petr Trunin, Muhammad Sunny Nazeer, Lucia Beccai, Perla Maiolino, Cecilia Laschi   +6 more
wiley   +1 more source

Accelerating Musculoskeletal Robotics Through Parametric Design and 3D‐Printed Flexible Structures

Advanced Intelligent Systems, EarlyView.
Parametric design and flexible 3D printing create muscle‐, tendon‐, ligament‐, and cushion‐like robotic elements from a single thermoplastic polyurethane material. Tuning lattice patterns adjusts regional mechanical properties and enables coordinated multijoint motions in a life‐sized musculoskeletal leg under external suspension, with partial body ...
Shunnosuke Yoshimura, Kento Kawaharazuka, Kei Okada   +2 more
wiley   +1 more source