Results 131 to 140 of about 78,355 (309)
Ischemic preconditioning: Protection against myocardial necrosis and apoptosis
Efstathios K Iliodromitis1, Antigone Lazou2, Dimitrios Th Kremastinos112nd University Department of Cardiology, Medical School, University of Athens, Greece; 2Lab of Animal Physiology, School of Biology, Aristotle University of Thessaloniki ...
Antigone Lazou +2 more
core
Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-akt pathway [PDF]
Brief intermittent episodes of ischemia and reperfusion, at the onset of reperfusion after a prolonged period of ischemia, confer cardioprotection, a phenomenon termed "ischemic postconditioning" (Postcond).
Tsang, A. +3 more
core
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source
FEniCSx-pctools: Tools for PETSc Block Linear Algebra Preconditioning in FEniCSx [PDF]
peer reviewedSolving partial differential equations with the finite element method leads to large linear systems of equations that must be solved. When these systems have a natural block structure due to multiple field variables, using iterative solvers ...
REHOR, Martin, HALE, Jack
core +1 more source
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang +19 more
wiley +1 more source
In response to ischemic/hypoxic preconditioning, tissues/ organs exhibit protective responses to subsequent and severe ischemic stress. We hypothesized that repetitive hypoxic preconditioning (RHP) may provide long-lasting protection than single ...
楊芝青;林隆慶;吳明修;鄭劍廷;賴明坤 +1 more
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The distribution and function of the ATP-sensitive potassium channel subunit Kir6.1 in cardiac and skeletal muscle cell lines. [PDF]
ATP-sensitive potassium channels (KAtp) are present in the plasma membrane of a number of tissues but are also present on endomembranes such as the endoplasmic reticulum (ER) and mitochondria.
Ng, K-E.
core
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Preconditioning and Parallel Preconditioning
We review current methods for preconditioning systems of equations for their solution using iterative methods. We consider the solution of unsymmetric as well as symmetric systems and discuss techniques and implementations that exploit parallelism.
Iain S. Duff +3 more
core

