Results 201 to 210 of about 78,355 (309)

Accurate Measurement in All‐inside Posterior Cruciate Ligament Reconstruction: A Technical Note

Arthroscopy Techniques, EarlyView.
Abstract With the increasing rate of posterior cruciate ligament reconstruction (PCLr) and growing adoption of the all‐inside PCLr, the existing literature lacks an optimal surgical protocol for this technique. It is well recognized that variations in knee size and intraoperative positioning pose challenges in determining the key parameter—the length ...
Daoliang Xu, Wei Yu, Zelin Jiang, Jianxia Wen, Xiaoyun Pan   +4 more
wiley   +1 more source

Bypassing the Blood-Brain Barrier: A Dual-Axis Framework for Alzheimer's Disease Utilizing Glymphatic-Lymphatic Clearance and In Situ Chaperone Synthesis. [PDF]

Cureus
Chen HW.
europepmc   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo. [PDF]

J Dent Sci
Nugraha AP, Hong G, Yang K, Narmada IB, Rantam FA, Ernawati DS, Ardani IGAW, Pramusita A, Putranti NAR, Fadzila NDR, Aurora AZS, Farizaldi RI, Luthfi M, Situmorang PC, Riawan W, Tanimoto K.   +15 more
europepmc   +1 more source

How curriculum modifications shape educational pathways: Evidence from linked administrative data in Switzerland

British Educational Research Journal, EarlyView.
Abstract The increasing heterogeneity of learning needs and preconditions in inclusive mainstream classrooms entails that not all learners are equally able to meet the regular learning objectives. In response, various integrative measures have been implemented to tailor instruction to students' individual needs.
Robin Benz, Caroline Sahli Lozano, Esperanza Marx   +2 more
wiley   +1 more source

Neddylation blockade protects endothelial cells against inflammation and ischemia-reperfusion injuries. [PDF]

Cell Commun Signal
Mayoral V, Braud P, Néel M, Vion AC, Vaillant M, Mesnard B, Haspot F, Le Bas-Bernardet S, Tilly G, Degauque N, Branchereau J, Blancho G, Bruneau S.   +12 more
europepmc   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Berberine-Pretreated Bone Marrow Mesenchymal Stem Cells Accelerate Skin Wound Healing in Rats With Burn Injuries. [PDF]

Int Wound J
Tan J, Chen C.
europepmc   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Low Dose Ketamine Preconditions Astrocyte Mitochondria to Achieve Antidepressant Efficacy via Adenosine, Humanin, and Melatonin Upregulation and Efflux. [PDF]

Alpha Psychiatry
Anderson G.
europepmc   +1 more source