Results 51 to 60 of about 2,534,918 (292)

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Intermittent predictive control of an inverted pendulum [PDF]

, 2006
Intermittent predictive pole-placement control is successfully applied to the constrained-state control of a prestabilised experimental inverted ...
Gawthrop, P.J., Wang, L.
core   +1 more source

Prediction in projection [PDF]

Chaos: An Interdisciplinary Journal of Nonlinear Science, 2015
Prediction models that capture and use the structure of state-space dynamics can be very effective. In practice, however, one rarely has access to full information about that structure, and accurate reconstruction of the dynamics from scalar time-series data—e.g., via delay-coordinate embedding—can be a real challenge.
Joshua Garland, Elizabeth Bradley
openaire   +3 more sources

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

CPT: Pharmacometrics & Systems Pharmacology
Optimal dosing in pregnant and lactating women requires an understanding of the pharmacokinetics in the mother, fetus, and breastfed infant. Physiologically‐based pharmacokinetic (PBPK) modeling can be used to simulate untested scenarios and hence ...
Jia Ning, Amita Pansari, Karen Rowland Yeo, Aki T. Heikkinen, Catriona Waitt, Lisa M. Almond   +5 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Identification and predictive control of a multistage evaporator [PDF]

, 2010
A recurrent neural network-based nonlinear model predictive control (NMPC) scheme in parallel with PI control loops is developed for a simulation model of an industrial-scale five-stage evaporator.
Cao, Y., Tadé, M.O., J.C. Atuonwu, Rangaiah, G., Atuonwu, J.C., Atuonwu, James C., Cao, Yi, Rangaiah, G.P., Y. Cao, Atuonwu, J., Tade, Moses, Tadé, M. O., M.O. Tadé, G.P. Rangaiah, Rangaiah, G. P.   +14 more
core   +1 more source

A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator

CPT: Pharmacometrics & Systems Pharmacology
The Simcyp Simulator is a software platform widely used in the pharmaceutical industry to conduct stochastic physiologically‐based pharmacokinetic (PBPK) modeling.
Liam Curry, Sarah Alrubia, Frederic Y. Bois, Ruth Clayton, Eman El‐Khateeb, Trevor N. Johnson, Muhammad Faisal, Sibylle Neuhoff, Kris Wragg, Amin Rostami‐Hodjegan   +9 more
doaj   +1 more source

Mechanistic Insights into Cytokine Antagonist-Drug Interactions: A Physiologically Based Pharmacokinetic Modelling Approach with Tocilizumab as a Case Study

Pharmaceutics
Background: Understanding interactions between cytokine antagonists and drugs is essential for effective medication management in inflammatory conditions.
Xian Pan, Cong Liu, Felix Stader, Abdallah Derbalah, Masoud Jamei, Iain Gardner   +5 more
doaj   +1 more source

The Biomarkers for Predicting Viral HepatitisAssociated Hepatocellular Carcinoma

The Turkish Journal of Gastroenterology, 2022
Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world, and more than half of the newly diagnosed cases are chronic hepatitis B patients.
Qing Yang, Changfeng Sun, Yunjian Sheng, Wen Chen, Cunliang Deng   +4 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source