Results 71 to 80 of about 127,481 (314)

One-Year Follow-Up of COVID-19 Patients Indicates Substantial Assay-Dependent Differences in the Kinetics of SARS-CoV-2 Antibodies

open access: yesMicrobiology Spectrum, 2022
Determination of antibody levels against the nucleocapsid (N) and spike (S) proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are used to estimate the humoral immune response after SARS-CoV-2 infection or vaccination.
Alexander E. Egger   +18 more
doaj   +1 more source

Synthesizing benchmarks for predictive modeling [PDF]

open access: yes2017 IEEE/ACM International Symposium on Code Generation and Optimization (CGO), 2017
Predictive modeling using machine learning is an effective method for building compiler heuristics, but there is a shortage of benchmarks. Typical machine learning experiments outside of the compilation field train over thousands or millions of examples.
Cummins, C   +3 more
openaire   +6 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Fuzzy model based predictive control of chemical processes. [PDF]

open access: yes, 1996
The past few years have witnessed a rapid growth in the use of fuzzy logic controllers for the control of processes which are complex and ill-defined. These control systems, inspired by the approximate reasoning capabilities of humans under conditions
Kandiah, Sivasothy
core  

Predictive modelling [PDF]

open access: yesForced Migration Review, 2008
Empirical modelling techniques are the only way to effectivelysimulate migration resulting from a complex combination ofpressures and opportunities.
Christopher Smith   +3 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Arrested Coalescence: A Tool to Explore Tissue Rheology

open access: yesBiophysica
Tissue spheroids are self-organised 3D cellular aggregates that serve as a versatile platform in tissue engineering. While numerous high-throughput methods exist to characterise the cellular function of tissue spheroids, equivalent techniques for the ...
Sotiris Samatas   +2 more
doaj   +1 more source

Predictive Model Selection

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1995
SUMMARY We consider the problem of selecting one model from a large class of plausible models. A predictive Bayesian viewpoint is advocated to avoid the specification of prior probabilities for the candidate models and the detailed interpretation of the parameters in each model.
Laud, Purushottam W., Ibrahim, Joseph G.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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