Results 91 to 100 of about 743,383 (345)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Application of Computational Intelligence Techniques to Process Industry Problems [PDF]
In the last two decades there has been a large progress in the computational intelligence research field. The fruits of the effort spent on the research in the discussed field are powerful techniques for pattern recognition, data mining, data modelling,
Gabrys, Bogdan, Kadlec, Petr
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Spatial-temporal data modelling and processing for personalised decision support [PDF]
The purpose of this research is to undertake the modelling of dynamic data without losing any of the temporal relationships, and to be able to predict likelihood of outcome as far in advance of actual occurrence as possible.
Othman, Muhaini
core
Universal Predictability of Mobility Patterns in Cities
Despite the long history of modelling human mobility, we continue to lack a highly accurate approach with low data requirements for predicting mobility patterns in cities.
Di, Zengru +4 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Credit Card Fraud Detection Using AdaBoost and Majority Voting
Credit card fraud is a serious problem in financial services. Billions of dollars are lost due to credit card fraud every year. There is a lack of research studies on analyzing real-world credit card data owing to confidentiality issues.
Kuldeep Randhawa +4 more
doaj +1 more source
Bayesian inference for bivariate ranks
A recommender system based on ranks is proposed, where an expert's ranking of a set of objects and a user's ranking of a subset of those objects are combined to make a prediction of the user's ranking of all objects.
Guillotte, Simon +2 more
core
Statistical Inference for Ordinal Predictors in Generalized Linear and Additive Models with Application to Bronchopulmonary Dysplasia [PDF]
Jan Gertheiss +3 more
openalex +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

