Results 151 to 160 of about 27,995 (239)

Diagnosis and Management of Nitazene Dependence in Sydney, Australia: A Case Series

Drug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Nitazenes are synthetic opioids with potent μ‐receptor activity. There are increasing reports of nitazene overdoses worldwide. We report on a case series of protonitazene and metonitazene dependence responding to high dose medication for the treatment of opioid dependence in both inpatient and outpatient settings.
Daniel Dutkiewicz, Hester Wilson, Peter Chisholm, Thanjira Jiranantakan, Christine Harvey, Kaniz Fatema, Mark Hardy   +6 more
wiley   +1 more source

Efficacy of Pregabalin versus Cinnarizine in Preventive Treatment of Children with Migraine Headache: A Randomized Double-Blind Clinical Trial Study. [PDF]

Iran J Child Neurol
Vafaee-Shahi M, Vaferi H, Ashrafi M, Riahi A, Mohammadzadeh A, Hadavi N, Kheirkhah D.   +6 more
europepmc   +1 more source

Regional Nerve Blocks and OnabotulinumtoxinA in the Management of Trigeminal Trophic Syndrome: A Case Report of a Novel Multimodal Approach

Oral Surgery, Volume 19, Issue 4, Page 370-372, November 2026.
ABSTRACT Objective Trigeminal trophic syndrome (TTS) is a rare condition caused by trigeminal nerve injury, classically characterized by anaesthesia, paresthesia and facial ulceration. We present two cases of TTS successfully managed with regional nerve blocks and onabotulinumtoxinA. Methods Two patients—a 54‐year‐old woman and a 65‐year‐old man—with a
Shamin Masrour, Rhea Sudhakaran
wiley   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn, Susanne Gradl, Vanessa Osterloh, Peter Gmeiner, Harald Hübner, Markus R. Heinrich   +5 more
wiley   +1 more source

Pregabalin and placebo responders show different effects on central pain processing in chronic pancreatitis patients

, 2015
Stefan AW Bouwense,1 Søren S Olesen,2 Asbjørn M Drewes,2 Harry van Goor,1 Oliver HG Wilder-Smith31Pain and Nociception Neuroscience Research Group, Department of Surgery, Radboud university medical center, Nijmegen, The Netherlands; 2Mech ...
Drewes AM, van Goor H, Bouwense SA, Olesen SS, Wilder-Smith OH   +4 more
core  

Comparative Effectiveness of Pregabalin With Duloxetine Versus Pregabalin With Amitriptyline in Chronic Low Back Pain With Radiculopathy: A Prospective Comparative Study. [PDF]

Health Sci Rep
Khanam SM, Sarker SK, Mullick AR, Anwar SNMR.   +3 more
europepmc   +1 more source

Individualized multimodal pain management for chronic perineal pain: A case report. [PDF]

Medicine (Baltimore)
Ren X, Cong L.
europepmc   +1 more source

Effect of <i>COMT</i> gene polymorphism on post-thoracotomy pain and analgesic requirements in patients receiving multimodal pre-emptive analgesia with pregabalin versus naproxen: A randomized clinical trial. [PDF]

Saudi J Anaesth
Das P, Gupta R, Singh V.
europepmc   +1 more source

Multicentre, 2×2 factorial, randomised, open-label trial of neuromodulators and cough control therapy for refractory or unexplained chronic cough: the FORTITUDE trial protocol. [PDF]

BMJ Open
Kum E, Hassan W, Beaudin S, Strong G, Smith K, Oliveira A, Al-Saiedy M, Mancopes R, Grave AS, Bernier M, Bhalla A, Brister DL, Côté A, Couillard S, Field SK, Johnston F, Newman R, Popovic N, Kaplan AG, Brooks D, Guyatt G, Satia I.   +21 more
europepmc   +1 more source

Efficacy and safety of mirogabalin in patients with fibromyalgia: protocol for a multicentre, Prospective, Randomised, Open-label, Blinded Endpoint (PROBE) study. [PDF]

BMJ Open
Liu M, Li Y, Yao X, Liang Y, Mao P, Huang Y, Zhang C, Li Y, Li C, Ma K, Li S, Zhang D, Luo F, Fan B.   +13 more
europepmc   +1 more source