Results 141 to 150 of about 21,312 (195)

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

open access: yesJournal of Evidence-Based Medicine, Volume 19, Issue 3, September 2026.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li   +7 more
wiley   +1 more source

A Comprehensive Scientometric Analysis of Placebo and Nocebo Effects in Pain Research: From Placebo Mechanisms to Clinical Trials

open access: yesJournal of Evaluation in Clinical Practice, Volume 32, Issue 6, September 2026.
ABSTRACT Placebo and nocebo phenomena are central in neuroscience, psychology, and clinical research, yet comprehensive bibliometric analyses remain limited. This study mapped placebo and nocebo research in pain, distinguishing mechanistic studies from randomised controlled trials (RCTs), using data from the Web of Science Core Collection up to March ...
Francesca Borghesi   +7 more
wiley   +1 more source

Impact of TCAs and Gabapentin on Saliva and BMI in Adults With Xerostomia

open access: yesJournal of Oral Rehabilitation, Volume 53, Issue 9, Page 1694-1702, September 2026.
In adults with medication‐related xerostomia, tricyclic antidepressant and gabapentin use were not independently associated with BMI or oral dryness after adjustment. Instead, female sex, anticholinergic burden, obstructive sleep apnea, GERD, thyroid disease, depression and race demonstrated stronger associations with reduced salivary flow and greater ...
Waldir Martineli Filho   +5 more
wiley   +1 more source

Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain. [PDF]

open access: yesCNS Neurosci Ther
Lu H   +22 more
europepmc   +1 more source

Pharmacokinetics of Orally Administered Clonidine in Dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 5, Page 450-456, September 2026.
ABSTRACT Clonidine is an α‐2 agonist shown to be both well tolerated and useful in the treatment of canine fear‐based disorders, although it is perceived to have a short duration of action. Clonidine is available in regular release and extended‐release formulations, but canine pharmacokinetic (PK) and pharmacodynamic (PD) data on any clonidine ...
Kevin Pflaum   +3 more
wiley   +1 more source

Gabapentinoid Poisoning Presentations to Victorian Emergency Departments: A 15‐Year Trend Analysis

open access: yesMedical Journal of Australia, Volume 224, Issue 9, September 2026.
ABSTRACT This study identified and characterised 1207 emergency department presentations related to gabapentinoid overdose in Victoria from 2009–2010 to 2023–2024. Presentation rates increased substantially since 2009–2010, and about half (49.5%; 597/1207) of all presentations were classified as intentional.
Bishaal Tej Gurung   +7 more
wiley   +1 more source

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