Results 121 to 130 of about 38,319 (245)

Optimising the Therapeutic Window: A Systematic Review and Network Meta‐Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Although pregabalin is a first‐line therapy for painful diabetic polyneuropathy (PDPN), its optimal dose–response relationship remains unclear. We conducted a network meta‐analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.
Doyun Kwon, Hee‐Jae Jung, Junho Nam, Jonghae Kim, Eonju Jeon, Sanggyu Kwak   +5 more
wiley   +1 more source

Incidence of somnolence and dizziness induced by mirogabalin and pregabalin under opioid treatment: a single-center observational study

Journal of Pharmaceutical Health Care and Sciences
Background The gabapentinoids pregabalin and mirogabalin are utilized to treat neuropathic pain, especially in patients with cancer receiving opioid analgesics. Pregabalin combined with strong opioids increases somnolence and dizziness, while mirogabalin
Hitoshi Iwasaki, Hiroshi Kato, Takenao Koseki, Masashi Kondo, Shigeki Yamada   +4 more
doaj   +1 more source

Efficacy and Safety of Pregabalin and Alpha‐Lipoic Acid Combination in Patients With Painful Diabetic Peripheral Neuropathy: A Randomized, Open‐Label, Non‐Inferiority, Phase IV Clinical Trial and Subgroup Analysis (OPTIMUM Study)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess the efficacy and safety of alpha‐lipoic acid (ALA) and pregabalin, both as mono and combination therapy, for treating painful diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus, with the hypothesis that pregabalin monotherapy is non‐inferior to combination therapy.
Tae Jung Oh, Sang Soo Kim, Seung‐Hwan Lee, Hyuk‐Sang Kwon, Eun Sook Kim, Eun‐Jung Rhee, Hye Jin Yoo, Han Na Jang, Woo Je Lee, Eun Sook Kim, Sang Yong Kim, Gwanpyo Koh, Eun‐Gyoung Hong, Tae Sun Park, Jong Chul Won   +14 more
wiley   +1 more source

Pregabalin for the management of fibromyalgia syndrome

Journal of Pain Research, 2010
Chad S BoomershineDepartment of Medicine, Vanderbilt University, Nashville, TN, USAAbstract: This last article in a three-part series on approved medications for managing fibromyalgia syndrome (FMS) reviews pregabalin (Lyrica®).
Chad S Boomershine
doaj  

Pregabalin Misuse and Abuse: A Scoping Review of Extant Literature [PDF]

Prescribing of pregabalin is increasing worldwide with public health concerns centering on misuse and abuse of prescribed and diverted pregabalin. To describe and map what is known about misuse and abuse of pregabalin, a scoping review of available ...
Al-Husseini, A, van Hout, MC, Wazaify, M
core   +1 more source

Chronic Insomnia and Excess Cannabis Ingestion in an Older Adult—A Clinical Report of Complex Geriatric Care

Journal of the American Geriatrics Society, EarlyView.
Cannabis use in older adults may have a broad range of effects in older adults impacting Mind, Mobility, Medications, Multi‐complexity, and what Matters Most.
Erik Fraunberger, Maia von Maltzahn
wiley   +1 more source

Association of perioperative initiation of gabapentin versus pregabalin with kidney function: a target trial emulation study

Frontiers in Medicine
BackgroundGabapentinoids, such as gabapentin and pregabalin, are opioid substitutes commonly included in perioperative multimodal analgesia regimens. We investigated whether the initiation of gabapentin and pregabalin during the perioperative period have
Yanfang He, Liqian Mo, Juan Li, Dongying Lu, Jinlei Niu, Ying Li, Qiying Zeng, Yueming Gao   +7 more
doaj   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

Evaluation of the effect of pregabalin on simulated driving ability using a driving simulator in healthy male volunteers

International Journal of General Medicine, 2014
Tomoaki Tujii, Win Thiri Kyaw, Hirotaka Iwaki, Noriko Nishikawa, Masahiro Nagai, Madoka Kubo, Masahiro Nomoto Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Tohon Ehime, Japan Abstract: Pregabalin, a ...
Tujii T, Kyaw WT, Iwaki H, Nishikawa N, Nagai M, Kubo M, Nomoto M   +6 more
doaj  

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner, Kevin Möri, Narayan Schütz, Philipp Buluschek, Tobias Nef   +4 more
wiley   +1 more source