Results 131 to 140 of about 38,319 (245)

Migraine and Restless Legs Syndrome: A Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio, Maria Cropano, Giada Panzino, Mariachiara Gaita, Giulio Cicarelli, Piero Barbanti, Gerardo Casucci, Simona Raimo, Antonio Costanzo   +8 more
wiley   +1 more source

A case report of pregabalin misuse leading to drug dependence

Frontiers in Psychiatry
Pregabalin misuse and dependence have become emerging concerns in recent years, particularly in regions where traditional drug-related crimes have been curbed, prompting users to seek alternative substances.
Yaan Luo, Yaan Luo, Xiafeng Zhou, Xiafeng Zhou, Ao Xiang, Ao Xiang, Yaqi Zeng, Yaqi Zeng, Jing Luo, Jing Luo, Bojie Zhou, Bojie Zhou, Nana Guo, Nana Guo, Xuhui Zhou   +14 more
doaj   +1 more source

Effects of Agomelatine on Sleep Across Populations: A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Agomelatine, a melatoninergic antidepressant, is often prescribed to improve sleep disturbance, though meta‐analytic evidence is currently lacking. This systematic review and meta‐analysis assessed its efficacy and tolerability in sleep outcomes compared to placebo.
Anastasios Stefanou, Ioannis Anastasiou, Panagiota Fallon, Eleni Glarou, Nikolaos Christodoulou, Andreas S. Lappas, Vasilios‐Panteleimon Bozikas, Myrto T. Samara   +7 more
wiley   +1 more source

Characterization and Evaluation of the Cytotoxicity of Pregabalin Gels for Oral Application

Pharmaceuticals
The efficacy of pregabalin in pain treatment has led to the search for new formulations for its use through different routes of administration. This study aimed to prepare, characterize, and evaluate the cytotoxicity of pregabalin (PG) gels for topical ...
Gabriela Monteiro Barbosa Xavier, Lindalva Maria de Meneses Costa Ferreira, Marcele Fonseca Passos, Ana Paula Drummond Rodrigues, Felipe Tuji de Castro Franco, Cecy Martins Silva, José Otávio Carréra Silva Júnior, Roseane Maria Ribeiro-Costa, Jesuína Lamartine Nogueira Araújo   +8 more
doaj   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE IN PATIENTS-CONTROLLED IV ANALGESIA (PCIA) AFTER ORTHOPEDIC SURGERY [PDF]

Background: Optimal pain treatment with minimal side-effects is essential to allow early mobility, optimal functional recovery, and to reduce postoperative morbidity and mortality.
اخوان اکبری, قدرت, ایمانی, فرناد, حیدریان, مجید, رحیم زاده, پوپک, کبیری خداداد, پویا   +4 more
core  

Outcomes of 87 small‐breed dogs surgically treated for Chiari‐like malformation and syringomyelia

Veterinary Surgery, EarlyView.
Abstract Objective To report the outcomes of titanium mesh (TM) cranioplasty without polymethylmethacrylate (PMMA), incorporating a deliberate gap between the foramen magnum decompression (FMD) surface and the TM, in small‐breed dogs with Chiari‐like malformation and syringomyelia (CM/SM). Study design Retrospective clinical study.
Sung Su Park, Ji Young Park, Ho Jae Han
wiley   +1 more source

Pregabalin dependence: Experiences from liaison psychiatric settings in Kashmir, North India: A case series

Industrial Psychiatry Journal
Pregabalin, a gamma-aminobutyric acid (GABA) analog, is a new-generation antiepileptic that is approved for the treatment of neuropathic pain, fibromyalgia, partial seizures, and generalized anxiety disorder. There is a rising concern regarding its abuse
Aaliya Khanam, Rajnish Raj, Zaid A. Wani, Yasir H. Rather, Iqra Arshad   +4 more
doaj   +1 more source

The Changes Over 15 Years Within a Pediatric Chronic Pain Service

Paediatric and Neonatal Pain, Volume 8, Issue 2, June 2026.
ABSTRACT How do we know if a service is working? How has the presentation and management of children with chronic pain changed over the last fifteen years and what demonstrates adherence to changing guidelines? This audit of a large tertiary pediatric chronic pain service assessed relevant multivariate data gathered over the last 15 years to try to ...
Hadassah Buechner, Cameron Sanderson, Kit Min Chong, Amy Donaghy, Olivia Shand, Iona Lindsay, Mia Findlay, Ewan Wallace   +7 more
wiley   +1 more source

Restless Legs Syndrome in Patients With PMP22‐Related Neuropathies

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims Restless legs syndrome (RLS) is frequently reported in peripheral neuropathies, but its prevalence and clinical correlates in Charcot–Marie–Tooth disease type 1A (CMT1A) and hereditary neuropathy with liability to pressure palsies (HNPP) remain poorly defined.
Bogdan Bjelica, Milorad Vujnic, Milica Vukojevic, Ivo Bozovic, Nikola Andrejic, Ivana Basta, Vidosava Rakocevic‐Stojanovic, Stojan Peric   +7 more
wiley   +1 more source