Results 131 to 140 of about 31,350 (256)

Regional Nerve Blocks and OnabotulinumtoxinA in the Management of Trigeminal Trophic Syndrome: A Case Report of a Novel Multimodal Approach

open access: yesOral Surgery, EarlyView.
ABSTRACT Objective Trigeminal trophic syndrome (TTS) is a rare condition caused by trigeminal nerve injury, classically characterized by anaesthesia, paresthesia and facial ulceration. We present two cases of TTS successfully managed with regional nerve blocks and onabotulinumtoxinA. Methods Two patients—a 54‐year‐old woman and a 65‐year‐old man—with a
Shamin Masrour, Rhea Sudhakaran
wiley   +1 more source

Post‐ICU Psychotropic Medication Initiation in Nonagenarian Sepsis Survivors

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Yuichiro Shimoyama   +2 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

Exploiting the Reverse Function of Ene‐Reductase Enzymes in the Continuous Flow Synthesis of Naphthols From Tetralones

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
The development and optimization of a continuous flow method for the use of ERED enzymes in the reverse mode is presented to convert tetralones into naphthols using air as the terminal oxidant. Both solution‐phase and the immobilized enzyme were explored along with different reactor configurations leading to product yields of up to 83% in short ...
Ruairí Bannon   +6 more
wiley   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

open access: yesDrug Testing and Analysis, Volume 18, Issue 8, Page 1065-1075, August 2026.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis   +5 more
wiley   +1 more source

Trends and Characteristics of Opioid Use During Pregnancy Between 2010 and 2023: A French Nationwide Drug Utilization Study

open access: yesEuropean Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background While opioid use during pregnancy has raised concerns worldwide, population‐based data in Europe remain limited. In France, little is known about opioid use in the context of pregnancy. Methods We conducted a nationwide drug utilization study using the French EPI‐MERES Registry, derived from the National Health Data System (SNDS ...
Laurent Chouchana   +5 more
wiley   +1 more source

Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain. [PDF]

open access: yesCNS Neurosci Ther
Lu H   +22 more
europepmc   +1 more source

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