Results 11 to 20 of about 598 (175)

Novel 17 Substituted Pregnadiene Derivatives as 5.ALPHA.-Reductase Inhibitors and Their Binding Affinity for the Androgen Receptor

Chemical and Pharmaceutical Bulletin, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Marisa Cabeza, Eugenio Flores, Ivonne Heuze, Mauricio Sánchez, Eugene Bratoeff, Elena Ramı́rez, Victor Alfonso Francolugo   +6 more
openalex   +4 more sources

Urinary and biliary metabolites of 17.ALPHA.-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione in the rabbit.

Chemical and Pharmaceutical Bulletin, 1974
Ten metabolites of 17α-acetoxy-6-chloro-4, 6-pregnadiene-3, 20-dione were isolated from urine and bile of the rabbit and their chemical structures were determined. The urinary main metabolite was 17α-acetoxy-2ξ, 3ξ-dihydroxy-5ξ-pregnan-20-one. The biliary main metabolite was 17α-acetoxy-6-chloro-2ξ, 3ξ-dihydroxy-4, 6-pregnadien-20-one. The administered
Tatsuya Abe, Akira Kambegawa
openalex   +4 more sources

The pathogenic actinobacterium Rhodococcus equi: what's in a name? [PDF]

Mol Microbiol, 2019
Vázquez-Boland JA, Meijer WG.
europepmc   +3 more sources

Synthesis of 20α- and 20β-Amino-3, 5-pregnadiene Derivatives and Antimicrobial Activity

Agricultural and Biological Chemistry, 1970
Y. NAGAI, Yuichiro Kurosawa
openalex   +3 more sources

Intraocular pressure effects of common topical steroids for post-cataract inflammation: are they all the same? [PDF]

Ophthalmol Ther, 2013
Pleyer U, Ursell PG, Rama P.
europepmc   +2 more sources

On the formation of allenes in the steroid series II. Synthesis and structure of several 19-nor-17,20-pregnadienes

, 1971
Benn, Cohen, Gilman, Hoff, Jacobs, Oppenauer, Rona, Rona, Taylor, Waters   +9 more
core   +2 more sources

Study on the Potential Molecular Mechanism of Xihuang Pill in the Treatment of Pancreatic Cancer Based on Network Pharmacology and Bioinformatics

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Objective. We aimed to analyze the possible molecular mechanism of Xihuang pill (XHP) in the treatment of pancreatic cancer based on methods of network pharmacology, molecular docking, and bioinformatics. Methods. The main active components and targets were obtained through the TCMSP database, the BATMAN‐TCM database, and the Chemistry database.
Jing Wang, Yaxing Zhang, Qiuyuan Wang, Luyao Wang, Peitong Zhang, Lu sa Mota da Silva   +5 more
wiley   +1 more source

PYED-1 Overcomes Colistin Resistance in Acinetobacter baumannii

Pathogens, 2023
Antibiotic resistance has become more and more widespread over the recent decades, becoming a major global health problem and causing colistin to be increasingly used as an antibiotic of last resort.
Maria Stabile, A. Esposito, V. Iula, Annalisa Guaragna, E. De Gregorio   +4 more
semanticscholar   +1 more source

Ten years of marine natural products research at Rhodes University [PDF]

, 2004
Marine invertebrates, algae and microorganisms produce a plethora of structurally unique and biologically active secondary metabolites. The ecological roles of these natural products, although not completely understood, range from chemical defence ...
Beukes, Denzil R, Davies-Coleman, Michael T   +1 more
core   +2 more sources

The Glucocorticoid PYED-1 Disrupts Mature Biofilms of Candida spp. and Inhibits Hyphal Development in Candida albicans

Antibiotics, 2021
Invasive Candida infections have become a global public health problem due to the increase of Candida species resistant against antifungal therapeutics.
A. Esposito, A. Migliaccio, V. Iula, R. Zarrilli, Annalisa Guaragna, E. De Gregorio   +5 more
semanticscholar   +1 more source