Results 11 to 20 of about 586 (172)
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Objective. We aimed to analyze the possible molecular mechanism of Xihuang pill (XHP) in the treatment of pancreatic cancer based on methods of network pharmacology, molecular docking, and bioinformatics. Methods. The main active components and targets were obtained through the TCMSP database, the BATMAN‐TCM database, and the Chemistry database.
Jing Wang +5 more
wiley +1 more source
PYED-1 Overcomes Colistin Resistance in Acinetobacter baumannii
Pathogens, 2023 Antibiotic resistance has become more and more widespread over the recent decades, becoming a major global health problem and causing colistin to be increasingly used as an antibiotic of last resort.
Maria Stabile +4 more
semanticscholar +1 more source
Antibiotics, 2021 Invasive Candida infections have become a global public health problem due to the increase of Candida species resistant against antifungal therapeutics.
A. Esposito +5 more
semanticscholar +1 more source
Steroid Derivatives as Potential Antimicrobial Agents against Staphylococcus aureus Planktonic Cells
Microorganisms, 2020 In this work, the antibacterial activity of deflazacort and several of its synthetic precursors was tested against a panel of bacterial pathogens responsible for most drug-resistant infections including Staphylococcus aureus, Enterococcus spp ...
Adriana Vollaro +6 more
semanticscholar +1 more source
PYED-1 Inhibits Biofilm Formation and Disrupts the Preformed Biofilm of Staphylococcus aureus
Antibiotics, 2020 Pregnadiene-11-hydroxy-16α,17α-epoxy-3,20-dione-1 (PYED-1), a heterocyclic corticosteroid derivative of deflazacort, exhibits broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria. Here, we investigated the effect of PYED-
Adriana Vollaro +5 more
semanticscholar +1 more source
Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements
BioMed Research International, Volume 2017, Issue 1, 2017., 2017 Pancreatic cancer is a type of common malignant tumors with high occurrence in the world. Most patients presented in clinic had pancreatic cancer at advanced stages. Furthermore, chemotherapy or radiotherapy had very limited success in treating pancreatic cancer.
Qingxi Yue +5 more
wiley +1 more source
Formulation and Evaluation of Guggul Lipid Nanovesicles for Transdermal Delivery of Aceclofenac
The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014 Context. Most new drugs have low water solubility and liposome is an important formulation to administer such drugs; however, it is quite unstable and has negligible systemic absorption. Objective. Aceclofenac nanovesicles were made using guggul lipid for formulating stable transdermal formulation. Materials and Methods.
Praveen Kumar Gaur +4 more
wiley +1 more source
Antibiotics, 2020 Stenotrophomonas maltophilia, an environmental Gram-negative bacterium, is an emerging nosocomial opportunistic pathogen that causes life-threatening infections in immunocompromised patients and chronic pulmonary infections in cystic fibrosis patients ...
A. Esposito +6 more
semanticscholar +1 more source
Solid Lipid Nanoparticles of Guggul Lipid as Drug Carrier for Transdermal Drug Delivery
BioMed Research International, Volume 2013, Issue 1, 2013., 2013 Diclofenac sodium loaded solid lipid nanoparticles (SLNs) were formulated using guggul lipid as major lipid component and analyzed for physical parameters, permeation profile, and anti‐inflammatory activity. The SLNs were prepared using melt‐emulsion sonication/low temperature‐solidification method and characterized for physical parameters, in vitro ...
Praveen Kumar Gaur +3 more
wiley +1 more source
Nuclear Receptors in Nonalcoholic Fatty Liver Disease
Journal of Lipids, Volume 2012, Issue 1, 2012., 2012 Nuclear receptors comprise a superfamily of ligand‐activated transcription factors that are involved in important aspects of hepatic physiology and pathophysiology. There are about 48 nuclear receptors in the human. These nuclear receptors are regulators of many hepatic processes including hepatic lipid and glucose metabolism, bile acid homeostasis ...
Jorge A. López-Velázquez +5 more
wiley +1 more source